大肠杆菌噬菌体中对杀有害素和大肠杆菌素的耐受性及抗性的突变
Mutations to tolerance and resistance to pesticin and colicins in Escherichia coli phi.
作者信息
Ferber D M, Fowler J M, Brubaker R R
出版信息
J Bacteriol. 1981 May;146(2):506-11. doi: 10.1128/jb.146.2.506-511.1981.
Abstract
The universal colicin-indicator strain Escherichia coli phi, unlike E. coli strain K-12, is sensitive to pesticin, a bacteriocin produced by wild-type Yersinia pestis. Eleven distinct phenotypes of E. coli phi mutants were obtained by selection for insensitivity to pesticin, group B colicins, the group A colicin S4, or coliphage T5. Representative isolates from eight of these classes closely resembled resistant receptor mutants (Cir-, Fep-, and TonA-) or tolerant mutants (TonB-, ExbB-, ExbC-, Ivt-, and Cmt-) described in Escherichia coli K-12. The remainder were unique; of these, one resembled TonB- but was also tolerant to colicin S4 (TonB/S4-), and the others exhibited specific resistance to either colicin S4 (Sfr-) or to pesticin (Psr-). All receptor mutants except Psr- remained sensitive to pesticin, whereas TonB/S4, TonB-, ExbB-, and ExbC- isolates were highly tolerant to this bacteriocin.
摘要
通用的大肠杆菌噬菌素指示菌株大肠杆菌 phi 与大肠杆菌 K - 12 菌株不同，它对鼠疫菌素敏感，鼠疫菌素是野生型鼠疫耶尔森菌产生的一种细菌素。通过筛选对鼠疫菌素、B 组大肠杆菌素、A 组大肠杆菌素 S4 或噬菌体 T5 不敏感，获得了 11 种不同表型的大肠杆菌 phi 突变体。这些类别中的 8 个类别的代表性分离株与大肠杆菌 K - 12 中描述的抗性受体突变体（Cir -、Fep - 和 TonA -）或耐受性突变体（TonB -、ExbB -、ExbC -、Ivt - 和 Cmt -）非常相似。其余的则是独特的；其中一个类似于 TonB - 但也对大肠杆菌素 S4 具有耐受性（TonB/S4 -），其他的则对大肠杆菌素 S4（Sfr -）或鼠疫菌素（Psr -）表现出特异性抗性。除 Psr - 外，所有受体突变体对鼠疫菌素仍敏感，而 TonB/S4、TonB -、ExbB - 和 ExbC - 分离株对这种细菌素具有高度耐受性。
相似文献
1
Mutations to tolerance and resistance to pesticin and colicins in Escherichia coli phi.大肠杆菌噬菌体中对杀有害素和大肠杆菌素的耐受性及抗性的突变
J Bacteriol. 1981 May;146(2):506-11. doi: 10.1128/jb.146.2.506-511.1981.
2
Mode of action of pesticin.杀稻瘟菌素的作用模式。
J Bacteriol. 1969 May;98(2):359-67. doi: 10.1128/jb.98.2.359-367.1969.
3
Genetics of sensitivity of Salmonella species to colicin M and bacteriophages T5, T1, and ES18.沙门氏菌对大肠菌素M及噬菌体T5、T1和ES18敏感性的遗传学
J Bacteriol. 1977 Jun;130(3):1214-23. doi: 10.1128/jb.130.3.1214-1223.1977.
4
Characterization of group B colicin-resistant mutants of Escherichia coli K-12: colicin resistance and the role of enterochelin.大肠杆菌K-12的B组大肠菌素抗性突变体的特性：大肠菌素抗性与肠螯合素的作用
J Bacteriol. 1976 Jul;127(1):218-28. doi: 10.1128/jb.127.1.218-228.1976.
5
Genetics of resistance to colicins in Escherichia coli K-12: cross-resistance among colicins of group B.大肠杆菌K-12中对大肠杆菌素抗性的遗传学：B组大肠杆菌素之间的交叉抗性
J Bacteriol. 1975 Jul;123(1):96-101. doi: 10.1128/jb.123.1.96-101.1975.
6
The structurally related exbB and tolQ genes are interchangeable in conferring tonB-dependent colicin, bacteriophage, and albomycin sensitivity.结构相关的exbB和tolQ基因在赋予对tonB依赖性大肠杆菌素、噬菌体和白霉素敏感性方面是可互换的。
J Bacteriol. 1989 Nov;171(11):6387-90. doi: 10.1128/jb.171.11.6387-6390.1989.
7
Energy-coupled colicin transport through the outer membrane of Escherichia coli K-12: mutated TonB proteins alter receptor activities and colicin uptake.能量偶联的大肠杆菌K-12外膜上的大肠杆菌素转运：突变的TonB蛋白改变受体活性和大肠杆菌素摄取。
FEMS Microbiol Lett. 1994 Jun 1;119(1-2):65-70. doi: 10.1111/j.1574-6968.1994.tb06868.x.
8
Cross-resistance between bacteriophages and colicins in Escherichia coli K-12.大肠杆菌K-12中噬菌体与大肠杆菌素之间的交叉抗性
J Bacteriol. 1976 Jun;126(3):1347-50. doi: 10.1128/jb.126.3.1347-1350.1976.
9
Characterization of Escherichia coli mutants tolerant to bacteriocin JF246: two new classes of tolerant mutants.对耐受细菌素JF246的大肠杆菌突变体的表征：两类新的耐受突变体
J Bacteriol. 1973 Nov;116(2):885-92. doi: 10.1128/jb.116.2.885-892.1973.
10
Penetration of colicin M into cells of Escherichia coli.大肠杆菌素M对大肠杆菌细胞的穿透作用。
J Bacteriol. 1980 Apr;142(1):162-8. doi: 10.1128/jb.142.1.162-168.1980.
引用本文的文献
1
BipA is a novel regulator of pesticin and a type 6 secretion system.BipA是一种新型的杀鼠菌素和VI型分泌系统调节剂。
Infect Immun. 2025 Sep 9;93(9):e0019125. doi: 10.1128/iai.00191-25. Epub 2025 Aug 11.
2
Novel colicin Fy of Yersinia frederiksenii inhibits pathogenic Yersinia strains via YiuR-mediated reception, TonB import, and cell membrane pore formation.弗氏柠檬酸杆菌新型 colicin Fy 通过 YiuR 介导的接收、TonB 导入和细胞膜孔形成抑制致病性耶尔森氏菌。
J Bacteriol. 2012 Apr;194(8):1950-9. doi: 10.1128/JB.05885-11. Epub 2012 Feb 17.
3
Yersiniabactin iron uptake: mechanisms and role in Yersinia pestis pathogenesis.耶尔森菌素铁摄取：机制及其在鼠疫耶尔森氏菌发病机制中的作用。
Microbes Infect. 2011 Sep;13(10):808-17. doi: 10.1016/j.micinf.2011.04.008. Epub 2011 May 12.
4
The importance of the small RNA chaperone Hfq for growth of epidemic Yersinia pestis, but not Yersinia pseudotuberculosis, with implications for plague biology.小 RNA 伴侣蛋白 Hfq 对流行鼠疫耶尔森菌而非假结核耶尔森菌生长的重要性，这对鼠疫生物学具有重要意义。
J Bacteriol. 2010 Aug;192(16):4239-45. doi: 10.1128/JB.00504-10. Epub 2010 Jun 11.
5
Human- and plant-pathogenic Pseudomonas species produce bacteriocins exhibiting colicin M-like hydrolase activity towards peptidoglycan precursors.人类和植物致病的假单胞菌属物种产生对肽聚糖前体具有类大肠杆菌素M样水解酶活性的细菌素。
J Bacteriol. 2009 Jun;191(11):3657-64. doi: 10.1128/JB.01824-08. Epub 2009 Apr 3.
6
Colicin biology.大肠杆菌素生物学
Microbiol Mol Biol Rev. 2007 Mar;71(1):158-229. doi: 10.1128/MMBR.00036-06.
7
Yersinia pestis YbtU and YbtT are involved in synthesis of the siderophore yersiniabactin but have different effects on regulation.鼠疫耶尔森菌的YbtU和YbtT参与铁载体耶尔森菌素的合成，但对调控有不同影响。
Infect Immun. 2000 Aug;68(8):4452-61. doi: 10.1128/IAI.68.8.4452-4461.2000.
8
Characterization of colicin S4 and its receptor, OmpW, a minor protein of the Escherichia coli outer membrane.大肠杆菌素S4及其受体OmpW（大肠杆菌外膜中的一种次要蛋白质）的特性
J Bacteriol. 1999 Jun;181(11):3578-81. doi: 10.1128/JB.181.11.3578-3581.1999.
9
Colicins--exocellular lethal proteins of Escherichia coli.大肠杆菌素——大肠杆菌的胞外致死蛋白。
Folia Microbiol (Praha). 1998;43(6):563-82. doi: 10.1007/BF02816372.
10
Pesticin displays muramidase activity.杀有害物菌素具有溶菌酶活性。
J Bacteriol. 1997 Mar;179(5):1580-3. doi: 10.1128/jb.179.5.1580-1583.1997.
本文引用的文献
1
Pasteurella pestis: Role of Pesticin I and Iron in Experimental Plague.鼠疫耶尔森菌：鼠疫菌素I和铁在实验性鼠疫中的作用
Science. 1965 Jul 23;149(3682):422-4. doi: 10.1126/science.149.3682.422.
2
Iron-Binding Catechols and Virulence in Escherichia coli.铁结合儿茶酚与大肠杆菌的毒力。
Infect Immun. 1973 Mar;7(3):445-56. doi: 10.1128/iai.7.3.445-456.1973.
3
[Spontaneous formation of the colicine M producing mutants of Esch. coli V].[大肠杆菌V产大肠杆菌素M突变体的自发形成]
Antonie Van Leeuwenhoek. 1951;17(4):227-31. doi: 10.1007/BF02062267.
4
Pesticins. II. Production of pesticin I and II.杀真菌素。II. 杀真菌素I和II的产生
J Bacteriol. 1962 Sep;84(3):539-45. doi: 10.1128/jb.84.3.539-545.1962.
5
Pesticins. I. Pesticinbacterium interrelationships, and environmental factors influencing activity.杀昆虫素。一、杀昆虫素与细菌的相互关系以及影响活性的环境因素。
J Bacteriol. 1961 Dec;82(6):940-9. doi: 10.1128/jb.82.6.940-949.1961.
6
V and W antigens in strains of Pasteurella pseudotuberculosis.伪结核耶尔森氏菌菌株中的V抗原和W抗原。
Br J Exp Pathol. 1960 Feb;41(1):38-44.
7
Bacteriocin-like material produced by Pasteurella pestis.鼠疫耶尔森菌产生的类细菌素物质。
J Gen Microbiol. 1958 Oct;19(2):289-97. doi: 10.1099/00221287-19-2-289.
8
The virulence-enhancing effect of iron on nonpigmented mutants of virulent strains of Pasteurella pestis.铁对鼠疫耶尔森氏菌强毒株非色素突变体的毒力增强作用。
Br J Exp Pathol. 1956 Dec;37(6):577-83.
9
The pigmentation of Pasteurella pestis on a defined medium containing haemin.鼠疫耶尔森菌在含有血红素的特定培养基上的色素沉着。
Br J Exp Pathol. 1956 Dec;37(6):570-6.
10
Plasmids in Yersinia pestis.鼠疫耶尔森氏菌中的质粒
Infect Immun. 1981 Feb;31(2):839-41. doi: 10.1128/iai.31.2.839-841.1981.
Zotero 插件