Levi Marcel, Sivapalaratnam Suthesh
Department of Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands,
Intern Emerg Med. 2015 Apr;10(3):287-96. doi: 10.1007/s11739-014-1176-2. Epub 2014 Dec 24.
Hemostatic abnormalities frequently occur in critically ill patients and may vary from prolonged global clotting tests or isolated thrombocytopenia, to composite defects, such as consumption coagulopathies. There are many reasons for a disturbed coagulation in intensive care patients, and each of these underlying syndromes may require specific therapeutic intervention. Hence, an adequate differential diagnosis and initiation of proper (supportive) therapeutic strategies are critical to decrease morbidity and mortality in critically ill patients with hemostatic abnormalities.
止血异常在重症患者中经常出现,其范围可能从凝血试验延长或单纯血小板减少,到复合性缺陷,如消耗性凝血病。重症监护患者凝血功能紊乱有多种原因,每种潜在综合征可能都需要特定的治疗干预。因此,进行充分的鉴别诊断并启动适当的(支持性)治疗策略,对于降低有止血异常的重症患者的发病率和死亡率至关重要。