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一项关于Marjolin溃疡的十一年回顾性研究。

A Retrospective Study of Marjolin's Ulcer Over an Eleven Year Period.

作者信息

Challa Vasu Reddy, Deshmane Vijayalakshmi, Ashwatha Reddy Madhusudana Bommasandra

机构信息

Department of Surgical Oncology, Kidwai Memorial Institute of Oncology, Bengaluru, Karnataka, India.

出版信息

J Cutan Aesthet Surg. 2014 Jul;7(3):155-9. doi: 10.4103/0974-2077.146667.

Abstract

BACKGROUND

Marjolin's ulcer is a rare aggressive cutaneous malignancy occurring in previously occurred wounds. The most common aetiology is a burn wound involving extremities and squamous cell carcinoma is the most common variant.

MATERIALS AND METHODS

A retrospective analyses of medical records of patients treated in a single unit with a diagnosis of Marjolin's ulcer was performed.

RESULTS

During the study period, 14 patients were treated. Four patients had lymph node metastases and one had pulmonary metastases at the time of presentation. Seven patients underwent wide excision with reconstruction and seven underwent amputation or disarticulation because of advanced malignancy. During the follow up two patients developed local recurrence and one developed pulmonary metastases. Both the patients with pulmonary metastases had Marjolin's ulcer of trunk.

CONCLUSION

Marjolin's ulcer occurs more commonly in the extremities. Distant metastases occur commonly in patients with ulcers on the of trunk.

摘要

背景

马乔林溃疡是一种罕见的侵袭性皮肤恶性肿瘤,发生于既往伤口。最常见的病因是累及四肢的烧伤创面,最常见的病理类型是鳞状细胞癌。

材料与方法

对在单一科室接受治疗且诊断为马乔林溃疡的患者病历进行回顾性分析。

结果

在研究期间,共治疗14例患者。4例患者就诊时伴有淋巴结转移,1例伴有肺转移。7例患者接受了广泛切除并重建,7例因肿瘤进展接受了截肢或关节离断术。随访期间,2例患者出现局部复发,1例出现肺转移。发生肺转移的2例患者均为躯干马乔林溃疡。

结论

马乔林溃疡更常见于四肢。躯干溃疡患者常发生远处转移。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b256/4271295/fc533c63534d/JCAS-7-155-g001.jpg

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