Department of Mechanical and Mechatronics Engineering, University of Waterloo , Waterloo, Ontario N2L 3G1, Canada.
Biomicrofluidics. 2014 Oct 21;8(5):054120. doi: 10.1063/1.4899807. eCollection 2014 Sep.
A new microfluidic method that allows hydrodynamic focusing in a microchannel with two sheath flows is demonstrated. The microchannel network consists of a T-shaped main channel and two T-shaped branch channels. The flows of the sample stream and the sheath streams in the microchannel are generated by electroosmotic flow-induced pressure gradients. In comparison with other flow focusing methods, this novel method does not expose the sample to electrical field, and does not need any external pumps, tubing, and valves.
本文展示了一种新的微流控方法,该方法允许在具有两个鞘流的微通道中进行流体动力学聚焦。微通道网络由 T 形主通道和两个 T 形分支通道组成。微通道中样品流和鞘流的流动是由电渗流引起的压力梯度产生的。与其他流聚焦方法相比,这种新方法不会使样品暴露于电场中,也不需要任何外部泵、管道和阀门。