Teimouri Azam, Iraj Bijan, Amini Massoud, Hovsepian Silva
Department of Internal Medicine, Endocrine and Metabolism Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Department of Endocrinology, Endocrine and Metabolism Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Int J Prev Med. 2014 Nov;5(11):1432-8.
In this study, we evaluated the quality of care and control of cardiovascular risk factors in newly diagnosed diabetic patients, identified during diabetes screening program, 1 year after diagnosis.
In this prospective study, 83 newly diagnosed diabetic patients identified at screening in Isfahan, were studied. Height, weight, blood pressure, plasma glucose, lipids, and hemoglobin A1c (HbA1c) of these patients were measured 2 times, first at the time of diagnosis and then 1 year later, and the results were compared between two groups, with and without regular course of treatment.
Nearly 46.99% and 53.1% of the studied patients have regular and irregular course of treatment. After 1 year, significant improvement in the mean of plasma glucose, cholesterol, triglyceride, low density lipoprotein (LDL), high density lipoprotein and HbA1c was seen in patients with regular course of treatment except for blood pressure (P < 0.05). Frequency of controlled cardiovascular risk factors including fasting plasma glucose, HbA1c, cholesterol and LDL was significantly improved in patients with regular course of treatment (P < 0.05). Mentioned changes were not seen in patients with irregular course of treatment.
The findings of the current study demonstrated that though diabetes screening program result in earlier diagnosis of patients with type 2 diabetes, but it seems that regular follow-up and proper management of newly diagnosed patients is crucial for appropriate glycemic and metabolic control and preventing its related micro and macrovascular complication.
在本研究中，我们评估了在糖尿病筛查项目中确诊1年后新诊断糖尿病患者的心血管危险因素护理质量及控制情况。
在这项前瞻性研究中，对在伊斯法罕筛查中确诊的83例新诊断糖尿病患者进行了研究。对这些患者的身高、体重、血压、血糖、血脂和糖化血红蛋白（HbA1c）进行了两次测量，第一次在诊断时，然后在1年后，比较了接受正规治疗组和未接受正规治疗组两组之间的结果。
近46.99%和53.1%的研究患者接受正规和不正规治疗。1年后，接受正规治疗的患者除血压外，血糖、胆固醇、甘油三酯、低密度脂蛋白（LDL）、高密度脂蛋白和HbA1c的平均值有显著改善（P<0.05）。接受正规治疗的患者中，包括空腹血糖、HbA1c、胆固醇和LDL在内的心血管危险因素控制频率显著改善（P<0.05）。在接受不正规治疗的患者中未观察到上述变化。
本研究结果表明，虽然糖尿病筛查项目可使2型糖尿病患者得到早期诊断，但新诊断患者的定期随访和适当管理对于适当的血糖和代谢控制以及预防其相关的微血管和大血管并发症似乎至关重要。
