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牙周骨缺损中磷灰石陶瓷异体植入物的5年评估

5-year evaluation of durapatite ceramic alloplastic implants in periodontal osseous defects.

作者信息

Yukna R A, Mayer E T, Amos S M

机构信息

Louisiana State University, School of Dentistry, New Orleans.

出版信息

J Periodontol. 1989 Oct;60(10):544-51. doi: 10.1902/jop.1989.60.10.544.

DOI:10.1902/jop.1989.60.10.544
PMID:2553913
Abstract

Six patients who participated in a clinical study comparing the response of periodontal osseous defects to either grafting with Periograf (durapatite) hydroxylapatite (HA) ceramic or debridement alone (DEBR) were followed under an active maintenance program for 5 years. Mean values for gingival recession and attachment levels remained essentially stable following either treatment over the 5 year period. However, mean probeable pocket depths shifted from being significantly (P less than 0.05) shallower for DEBR sites at 6 months and 1 year to being significantly shallower for HA sites at 5 years. The probing pocket depth change for grafted sites was steady and the change from presurgical values was significantly greater than the change for DEBR areas, which became about 1.5 mm deeper over the 5 year postsurgical period. Intrapatient comparisons showed that recession, attachment gain, and pocket depth decrease were most frequently greater for the Periograf-treated sites. Assessment of the pattern of clinical changes during the 5 year postsurgical period demonstrated that the attachment level of grafted sites improved or stayed the same 86% of the time compared to only 62% stability or improvement in the DEBR only sites. In fact, 38% of the DEBR sites were worse at 5 years than at the time of surgery, a 3 times greater failure rate than that found in the HA-grafted sites. Pocket depth measurements showed that 98% of the Periograf-treated sites were better or the same as presurgically (2% worse), while only 80% of DEBR sites showed positive results and 20% had deeper pockets than at the time of surgery.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

六名参与临床研究的患者,该研究比较了牙周骨缺损对使用Periograf(磷酸三钙)羟基磷灰石(HA)陶瓷移植或单纯清创术(DEBR)的反应,在积极的维护计划下随访了5年。在5年期间,两种治疗后牙龈退缩和附着水平的平均值基本保持稳定。然而,平均可探及袋深度从6个月和1年时DEBR部位显著(P小于0.05)较浅,转变为5年时HA部位显著较浅。移植部位的探诊袋深度变化是稳定的,且与术前值相比的变化显著大于DEBR区域,后者在术后5年期间加深了约1.5毫米。患者内比较显示,Periograf治疗部位的退缩、附着增加和袋深度减小最常更大。对术后5年临床变化模式的评估表明,移植部位的附着水平有86%的时间得到改善或保持不变,而仅DEBR部位稳定性或改善的比例仅为62%。事实上,38%的DEBR部位在5年时比手术时更差,失败率是HA移植部位的3倍。袋深度测量显示,98%的Periograf治疗部位与术前相比更好或相同(2%更差),而只有80%的DEBR部位显示出阳性结果,20%的部位袋比手术时更深。(摘要截断于250字)

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