Comparative evaluation of the efficacy of synthetic nanocrystalline hydroxyapatite bone graft (Ostim) and synthetic microcrystalline hydroxyapatite bone graft (Osteogen) in the treatment of human periodontal intrabony defects: A clinical and denta scan study.

BACKGROUND

To evaluate the relative efficacy of synthetic nanocrystalline hydroxyapatite (HA) (Ostim) and microcrystalline HA (Osteogen) bone grafts in the treatment of human periodontal intrabony defects clinically and radiographically through denta scan.

MATERIALS AND METHODS

Ten chronic periodontitis patients with bilateral intrabony periodontal defects of ≥2 mm radiographic defect depth below 55 years of age were selected randomly and treated with synthetic nanocrystalline HA (Ostim) or synthetic microcrystalline HA (Osteogen) bone graft. Clinical parameters including probing depth (PD) and clinical attachment level (CAL) were measured preoperatively and postoperatively at 3 and 6 months for each of the defects using an occlusal acrylic stent. Radiographic parameters were measured with the help of denta scan preoperatively and postoperatively at 6 months.

RESULTS

At 6 months following therapy, the Osteogen group showed a reduction in mean PD from 11.10 ± 1.663 to 8.50 ± 0.850 mm and a change in mean CAL from 6.30 ± 1.160 to 3.40 ± 0.516 mm, whereas in the Ostim group, the mean PD decreased from 11.20 ± 0.919 to 8.30 ± 0.823 mm and mean CAL decreased from 6.10 ± 0.738 to 3.30 ± 0.483 mm. At 6 months following therapy, denta scan showed a reduction in mean intrabony defect depth in the Osteogen group from 2.54 ± 0.786 to 1.01 ± 0.448 mm, whereas in the Ostim group, it was 2.71 ± 0.650 mm to 1.12 ± 0.563 mm.

CONCLUSION

It was concluded that both the HA bone grafts produced statistically significant reduction in pocket depth, in the depth of osseous lesion, and a statistically significant gain in attachment level, irrespective of their physico-chemical properties.