Khasawneh Mohammad A, Shamp Andrea, Heller Stephanie, Zielinski Martin D, Jenkins Donald H, Osborn John B, Morris David S
From the Department of Surgery, Mayo Clinic, Rochester, Minnesota.
J Trauma Acute Care Surg. 2015 Jan;78(1):100-4. doi: 10.1097/TA.0000000000000498.
Interval cholecystectomy (IC) after percutaneous cholecystostomy tube (PCT) placement is the definitive treatment for cholecystitis in patients who are operative candidates after optimization of medical comorbidities. It is not clear, however, which patients will be able to have a laparoscopic IC after PCT placement. We aimed to identify factors associated with successful laparoscopic IC in these patients.
This is a retrospective review of patients who had a PCT from 2009 to 2011. Patient's baseline demographics, clinical data, and outcomes were analyzed. Univariable and multivariable comparisons were performed between patients who did and did not undergo IC. A subgroup analysis of patients who had laparoscopic IC and open IC was performed. Data are presented as percentages, medians with interquartile ranges (IQRs), or odds ratios with 95% confidence interval as appropriate.
A total of 245 patients had PCT placement, with a median age of 71 years (IQR, 59-80 years); 63% were male, of whom 72 (29%) underwent IC. The median time from PCT placement to IC was 55 days (IQR, 42-75 days). IC patients had a lower Charlson Comorbidity Index (5 [4-6] vs. 6 [4-8], p = 0.005) at the time of PCT placement. When controlling for other factors, lower Charlson Comorbidity Index and fewer previous abdominal operations were associated with performance of IC. Laparoscopic surgery was planned for 89% of the patients and completed successfully in 78%. The only factor associated with successful laparoscopic IC was fewer previous abdominal operations.
Patients who have been medically optimized following PCT can undergo laparoscopic IC with a high rate of success. The degree of illness at the time of PCT placement did not seem to influence the rate of success of laparoscopic IC.
Therapeutic/care management study, level III.
经皮胆囊造瘘管(PCT)置入术后行间隔期胆囊切除术(IC)是在合并症得到优化后适合手术的胆囊炎患者的确定性治疗方法。然而,尚不清楚哪些患者在PCT置入后能够接受腹腔镜IC。我们旨在确定这些患者中与成功的腹腔镜IC相关的因素。
这是一项对2009年至2011年期间接受PCT的患者的回顾性研究。分析了患者的基线人口统计学、临床数据和结局。对接受和未接受IC的患者进行单变量和多变量比较。对接受腹腔镜IC和开放IC的患者进行亚组分析。数据以百分比、四分位间距(IQR)表示的中位数或适当的95%置信区间的比值比呈现。
共有245例患者接受了PCT置入,中位年龄为71岁(IQR,59 - 80岁);63%为男性,其中72例(29%)接受了IC。从PCT置入到IC的中位时间为55天(IQR,42 - 75天)。IC患者在PCT置入时的Charlson合并症指数较低(5[4 - 6]对6[4 - 8],p = 0.005)。在控制其他因素时,较低的Charlson合并症指数和较少的既往腹部手术与IC的实施相关。89%的患者计划行腹腔镜手术,78%成功完成。与成功的腹腔镜IC相关的唯一因素是较少的既往腹部手术。
PCT后经医学优化的患者可以成功地接受腹腔镜IC。PCT置入时的疾病严重程度似乎不影响腹腔镜IC的成功率。
治疗/护理管理研究,III级。