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经皮胆囊造瘘管用于急性胆囊炎的使用变化趋势和结果。

Changing trends and outcomes in the use of percutaneous cholecystostomy tubes for acute cholecystitis.

机构信息

Department of Medical Education, Gundersen Health System, La Crosse, WI, USA.

出版信息

Ann Surg. 2013 Jun;257(6):1112-5. doi: 10.1097/SLA.0b013e318274779c.

Abstract

BACKGROUND

Percutaneous cholecystostomy tube (PCT) placement serves as a treatment option for acute cholecystitis in elderly and critically ill patients. The objective of this study was to compare PCT and cholecystectomy outcomes over time.

METHODS

PCTs placed from April 1, 1998, to December 31, 2009 (time period 2) were retrospectively reviewed. Patients who underwent cholecystectomies served as matched controls. Institutional data from March 1, 1989, to March 31, 1998 (time period 1) were reviewed to compare trends.

RESULTS

A total of 143 patients successfully underwent PCT placement in time period 2. When compared with patients undergoing cholecystectomy, PCT patients had a higher rate of cardiovascular disease (66% vs 26%, P = 0.001), diabetes (27% vs 13%, P = 0.001), and a higher mean Charlson comorbidity index (3.27 vs 1.07, P = 0.001). Compared with the first time period, patients undergoing PCT in the second time period had lower American Society of Anesthesiologist's classifications (American Society of Anesthesiologist's class I, II: 0% vs 18%, P = 0.001). Thirty-day mortality decreased from 36% to 12% in patients undergoing PCT (P = 0.001).

CONCLUSIONS

Among patients with acute cholecystitis, percutaneous cholecystostomy tubes were placed in older patients with increased comorbidities compared to cholecystectomy. Mortality rates after PCT decreased over time.

摘要

背景

经皮胆囊造瘘术 (PCT) 是老年和重症患者急性胆囊炎的治疗选择。本研究的目的是比较随时间推移 PCT 和胆囊切除术的结果。

方法

回顾性分析 1998 年 4 月 1 日至 2009 年 12 月 31 日(时间段 2)期间放置的 PCT。接受胆囊切除术的患者作为匹配对照。还回顾了 1989 年 3 月 1 日至 1998 年 3 月 31 日(时间段 1)的机构数据,以比较趋势。

结果

在时间段 2 中,共有 143 例患者成功进行了 PCT 放置。与接受胆囊切除术的患者相比,PCT 患者的心血管疾病发生率更高(66% vs 26%,P = 0.001),糖尿病发生率更高(27% vs 13%,P = 0.001),Charlson 合并症指数的平均值更高(3.27 vs 1.07,P = 0.001)。与第一个时间段相比,第二个时间段接受 PCT 的患者的美国麻醉医师协会分类较低(美国麻醉医师协会分类 I、II:0% vs 18%,P = 0.001)。接受 PCT 的患者的 30 天死亡率从 36%降至 12%(P = 0.001)。

结论

在患有急性胆囊炎的患者中,与胆囊切除术相比,经皮胆囊造瘘术更常用于患有更多合并症的老年患者。接受 PCT 治疗后的死亡率随时间推移而降低。

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