Alonso-Álvarez María Luz, Terán-Santos Joaquin, Ordax Carbajo Estrella, Cordero-Guevara José Aurelio, Navazo-Egüia Ana Isabel, Kheirandish-Gozal Leila, Gozal David
Sleep Unit, Burgos, Spain.
Sleep Unit, Burgos, Spain; CIBER of Respiratory Diseases, Burgos, Spain.
Chest. 2015 Apr;147(4):1020-1028. doi: 10.1378/chest.14-1959.
The objective of this study was to evaluate the diagnostic reliability of home respiratory polygraphy (HRP) in children with a clinical suspicion of OSA-hypopnea syndrome (OSAS).
A prospective blind evaluation was performed. Children between the ages of 2 to 14 years with clinical suspicion of OSAS who were referred to the Sleep Unit were included. An initial HRP followed by a later date, same night, in-laboratory overnight respiratory polygraphy and polysomnography (PSG) in the sleep laboratory were performed. The apnea-hypopnea index (AHI)-HRP was compared with AHI-PSG, and therapeutic decisions based on AHI-HRP and AHI-PSG were analyzed using intraclass correlation coefficients, Bland-Altman plots, and receiver operator curves (ROCs).
Twenty-seven boys and 23 girls, with a mean age of 5.3 ± 2.5 years, were studied, and 66% were diagnosed with OSAS based on a PSG-defined obstructive respiratory disturbance index ≥ 3/h total sleep time. Based on the availability of concurrent HRP-PSG recordings, the optimal AHI-HRP corresponding to the PSG-defined OSAS criterion was established as ≥ 5.6/h The latter exhibited a sensitivity of 90.9% (95% CI, 79.6%-100%) and a specificity of 94.1% (95% CI, 80%-100%).
HRP recordings emerge as a potentially useful and reliable approach for the diagnosis of OSAS in children. However, more research is required for the diagnosis of mild OSAS using HRP in children.
本研究的目的是评估家庭呼吸多导睡眠图(HRP)对临床怀疑患有阻塞性睡眠呼吸暂停低通气综合征(OSAS)儿童的诊断可靠性。
进行前瞻性盲法评估。纳入年龄在2至14岁之间、临床怀疑患有OSAS且被转诊至睡眠科的儿童。首先进行一次HRP,随后在同一天晚上在睡眠实验室进行实验室过夜呼吸多导睡眠图和多导睡眠监测(PSG)。将呼吸暂停低通气指数(AHI)-HRP与AHI-PSG进行比较,并使用组内相关系数、Bland-Altman图和受试者操作特征曲线(ROC)分析基于AHI-HRP和AHI-PSG的治疗决策。
共研究了27名男孩和23名女孩,平均年龄为5.3±2.5岁,其中66%根据PSG定义的阻塞性呼吸紊乱指数≥3次/小时总睡眠时间被诊断为OSAS。根据同时进行的HRP-PSG记录的可用性,将对应于PSG定义的OSAS标准的最佳AHI-HRP确定为≥5.6次/小时。后者的敏感性为90.9%(95%CI,79.6%-100%),特异性为94.1%(95%CI,80%-100%)。
HRP记录成为诊断儿童OSAS的一种潜在有用且可靠的方法。然而,对于使用HRP诊断儿童轻度OSAS还需要更多的研究。