1Centre for Health, Exercise and Sports Medicine, Department of Physiotherapy, School of Health Sciences, University of Melbourne, Melbourne, Victoria, AUSTRALIA; 2Research Unit for Musculoskeletal Function and Physiotherapy, Institute of Sports Science and Clinical Biomechanics, University of Southern Denmark, Odense, DENMARK; 3Department of Physiotherapy, School of Health and Rehabilitation Sciences, University of Queensland, St. Lucia, Brisbane, Queensland, AUSTRALIA; and 4Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Cabrini Institute, Malvern, Victoria, AUSTRALIA.
Med Sci Sports Exerc. 2015 Aug;47(8):1557-66. doi: 10.1249/MSS.0000000000000596.
This study aimed to evaluate the effects of a 12-wk, home-based, physiotherapist-guided neuromuscular exercise program on the knee adduction moment (an indicator of mediolateral knee load distribution) in people with a medial arthroscopic partial meniscectomy (APM) within the past 3-12 months.
An assessor-blinded, randomized controlled trial including people age 30-50 yr with no to mild pain after medial APM was conducted. Participants were randomly allocated to either a 12-wk neuromuscular exercise program that targeted neutral lower limb alignment or a control group with no exercise. The exercise program included eight individual sessions with one of seven physiotherapists in private clinics, together with home exercises. Primary outcomes were the peak external knee adduction moment during normal-paced walking and during one-leg sit-to-stand. Secondary outcomes included additional measures of knee joint load distribution, patient-reported outcomes, maximal knee and hip muscle strength, and physical function measures.
Of 62 randomized participants, 60 (97%) completed the trial. There were no significant between-group differences in the change in peak knee adduction moment during normal-paced walking (mean difference (95% confidence interval), 0.22 (-0.11 to 0.55) N·m/body weight × height %, P =0.19) or during one-leg sit-to-stand (-0.01 (-0.33 to 0.31) N·m/body weight × height %, P = 0.95). There were also no significant between-group differences for any of the secondary outcomes.
In patients 3-12 months after a medial APM, a neuromuscular exercise program did not alter the peak knee adduction moment, a key predictor of osteoarthritis structural disease progression. (Australia and New Zealand Clinical Trials Registry, #ACTRN12612000542897.).
本研究旨在评估为期 12 周、基于家庭、由物理治疗师指导的神经肌肉锻炼方案对过去 3-12 个月内接受内侧关节镜部分半月板切除术(APM)的人群的膝关节内收力矩(一种衡量膝关节内外侧负荷分布的指标)的影响。
进行了一项评估者盲法、随机对照试验,纳入了年龄在 30-50 岁之间、内侧 APM 后无至轻度疼痛的人群。参与者被随机分配到 12 周的神经肌肉锻炼方案组或无锻炼的对照组。锻炼方案包括在私人诊所由 7 名物理治疗师中的 1 名进行的 8 次个别课程,以及家庭锻炼。主要结局指标是正常步速行走和单腿坐站时的最大膝关节外展力矩。次要结局指标包括膝关节负荷分布的其他测量指标、患者报告的结局、最大膝关节和髋关节肌肉力量以及身体功能测量指标。
在 62 名随机参与者中,有 60 名(97%)完成了试验。在正常步速行走时的峰值膝关节内收力矩(平均差异(95%置信区间),0.22(-0.11 至 0.55)N·m/体重×身高%,P=0.19)或单腿坐站时的峰值膝关节内收力矩(-0.01(-0.33 至 0.31)N·m/体重×身高%,P=0.95)方面,两组之间没有显著的差异。对于任何次要结局指标,两组之间也没有显著差异。
在接受内侧 APM 后 3-12 个月的患者中,神经肌肉锻炼方案并未改变膝关节内收力矩,这是骨关节炎结构疾病进展的一个关键预测指标。(澳大利亚和新西兰临床试验注册处,#ACTRN12612000542897。)