Sullivan Matthew B
Department of Ecology and Evolutionary Biology, University of Arizona, Tucson Arizona, USA
J Virol. 2015 Mar;89(5):2459-61. doi: 10.1128/JVI.03289-14. Epub 2014 Dec 24.
Microbes have recently been recognized as dominant forces in nature, with studies benefiting from gene markers that can be quickly, informatively, and universally surveyed. Viruses, where explored, have proven to be powerful modulators of locally and globally important microbes through mortality, horizontal gene transfer, and metabolic reprogramming. However, community-wide virus studies have been challenged by the lack of a universal marker. Here, I propose that viral metagenomics has advanced to largely take over study of double-stranded DNA viruses.
微生物最近被公认为自然界中的主导力量，相关研究受益于能够快速、提供丰富信息且能进行广泛调查的基因标记。在已探索的领域中，病毒已被证明是通过致死作用、水平基因转移和代谢重编程，对局部和全球范围内重要微生物具有强大调节作用的因子。然而，全群落病毒研究一直受到缺乏通用标记的挑战。在此，我提出病毒宏基因组学已取得进展，在很大程度上可以接管双链DNA病毒的研究。
