Genomic responses to inflammation in mouse models mimic humans: we concur, apples to oranges comparisons won't do.
作者信息
Shay Tal, Lederer James A, Benoist Christophe
机构信息
Department of Life Sciences, Ben-Gurion University of the Negev, Be'er Sheva, 8410501 Israel;
Department of Surgery, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115; and.
出版信息
Proc Natl Acad Sci U S A. 2015 Jan 27;112(4):E346. doi: 10.1073/pnas.1416629111. Epub 2014 Dec 24.
Abstract
摘要
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Genomic responses to inflammation in mouse models mimic humans: we concur, apples to oranges comparisons won't do.小鼠模型中对炎症的基因组反应与人类相似：我们同意，不恰当的比较是不可行的。
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本文引用的文献
1
Genomic responses in mouse models greatly mimic human inflammatory diseases.小鼠模型中的基因组反应极大地模拟了人类炎症性疾病。
Proc Natl Acad Sci U S A. 2015 Jan 27;112(4):1167-72. doi: 10.1073/pnas.1401965111. Epub 2014 Aug 4.
2
Genomic responses in mouse models poorly mimic human inflammatory diseases.小鼠模型中的基因组反应与人类炎症性疾病的反应相差很大。
Proc Natl Acad Sci U S A. 2013 Feb 26;110(9):3507-12. doi: 10.1073/pnas.1222878110. Epub 2013 Feb 11.
3
Conservation and divergence in the transcriptional programs of the human and mouse immune systems.人类和小鼠免疫系统转录程序的保守性和分化。
Proc Natl Acad Sci U S A. 2013 Feb 19;110(8):2946-51. doi: 10.1073/pnas.1222738110. Epub 2013 Feb 4.
4
A comprehensive review of interventions in the NOD mouse and implications for translation.对非肥胖糖尿病（NOD）小鼠干预措施的全面综述及其转化意义。
Immunity. 2005 Aug;23(2):115-26. doi: 10.1016/j.immuni.2005.08.002.
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Statistical significance for genomewide studies.全基因组研究的统计学显著性
Proc Natl Acad Sci U S A. 2003 Aug 5;100(16):9440-5. doi: 10.1073/pnas.1530509100. Epub 2003 Jul 25.
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