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Physiology and molecular biology of the renal Na/H antiporter.

作者信息

Krapf R

机构信息

Department of Medicine, Insel University Hospital, Berne, Switzerland.

出版信息

Klin Wochenschr. 1989 Sep 1;67(17):847-51. doi: 10.1007/BF01717338.

Abstract

The renal Na/H antiporter is involved in cell pH regulation and, predominantly in the proximal tubule, also mediates transcellular NaCl and NaHCO3 transport. The transporter is regulated by systemic acid-base factors and hormones such as angiotensin II, PTH, glucocorticoids and alpha2-adrenergics. The human gene of the Na/H antiporter has been cloned and sequenced recently.

摘要

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