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移植后淋巴组织增生性疾病患者的坏死性淋巴瘤:超声与 CT 表现及其病理相关性

Necrotic lymphoma in a patient with post-transplantation lymphoproliferative disorder: ultrasonography and CT findings with pathologic correlation.

机构信息

Department of Radiology, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea ; Research Institute of Radiological Science, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.

Department of Pathology, Severance Hospital, Yonsei University College of medicine, Seoul, Korea.

出版信息

Ultrasonography. 2015 Apr;34(2):148-52. doi: 10.14366/usg.14050. Epub 2014 Dec 1.

Abstract

Seventeen months after kidney transplantation for the treatment of nephrotic syndrome, a retroperitoneal mass was incidentally detected in a 30-year-old man during routine follow-up. Ultrasonography revealed a mass measuring 5.5 cm×4.3 cm located between the liver and the atrophic right kidney, which showed markedly heterogeneous internal echogenicity. Contrast-enhanced computed tomography displayed a mild degree of enhancement only at the periphery of the mass, while the center lacked perceivable intensification. The patient underwent surgical resection. The final pathological diagnosis was non-Hodgkin lymphoma (diffuse large B-cell lymphoma), and extensive necrosis was observed on microscopic examination. We found that the prominent heterogeneous echogenicity of the mass (an unusual finding of lymphoma) demonstrated on ultrasonography is a result of extensive necrosis, which may sometimes occur in patients with post-transplantation lymphoproliferative disorder.

摘要

一名 30 岁男性在接受肾移植治疗肾病综合征 17 个月后,于常规随访中偶然发现腹膜后肿块。超声检查显示肝脏和萎缩右肾之间有一个 5.5cm×4.3cm 的肿块,内部回声明显不均匀。增强 CT 显示肿块仅在外周有轻度强化,而中心无明显强化。患者接受了手术切除。最终的病理诊断为非霍奇金淋巴瘤(弥漫性大 B 细胞淋巴瘤),显微镜下观察到广泛坏死。我们发现超声显示肿块显著不均匀回声(淋巴瘤的一个不常见表现)是广泛坏死的结果,这种情况在移植后淋巴组织增生性疾病患者中有时会出现。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0eb0/4372711/83f040ac53f6/usg-14050-f1.jpg

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