Department of Radiology, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea ; Research Institute of Radiological Science, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.
Department of Pathology, Severance Hospital, Yonsei University College of medicine, Seoul, Korea.
Ultrasonography. 2015 Apr;34(2):148-52. doi: 10.14366/usg.14050. Epub 2014 Dec 1.
Seventeen months after kidney transplantation for the treatment of nephrotic syndrome, a retroperitoneal mass was incidentally detected in a 30-year-old man during routine follow-up. Ultrasonography revealed a mass measuring 5.5 cm×4.3 cm located between the liver and the atrophic right kidney, which showed markedly heterogeneous internal echogenicity. Contrast-enhanced computed tomography displayed a mild degree of enhancement only at the periphery of the mass, while the center lacked perceivable intensification. The patient underwent surgical resection. The final pathological diagnosis was non-Hodgkin lymphoma (diffuse large B-cell lymphoma), and extensive necrosis was observed on microscopic examination. We found that the prominent heterogeneous echogenicity of the mass (an unusual finding of lymphoma) demonstrated on ultrasonography is a result of extensive necrosis, which may sometimes occur in patients with post-transplantation lymphoproliferative disorder.
一名 30 岁男性在接受肾移植治疗肾病综合征 17 个月后,于常规随访中偶然发现腹膜后肿块。超声检查显示肝脏和萎缩右肾之间有一个 5.5cm×4.3cm 的肿块,内部回声明显不均匀。增强 CT 显示肿块仅在外周有轻度强化,而中心无明显强化。患者接受了手术切除。最终的病理诊断为非霍奇金淋巴瘤(弥漫性大 B 细胞淋巴瘤),显微镜下观察到广泛坏死。我们发现超声显示肿块显著不均匀回声(淋巴瘤的一个不常见表现)是广泛坏死的结果,这种情况在移植后淋巴组织增生性疾病患者中有时会出现。