肌醇1,4,5-三磷酸结合蛋白P400的一级结构与功能表达
Primary structure and functional expression of the inositol 1,4,5-trisphosphate-binding protein P400.
作者信息
Furuichi T, Yoshikawa S, Miyawaki A, Wada K, Maeda N, Mikoshiba K
机构信息
Division of Behavior and Neurobiology, National Institute for Basic Biology, Okazaki, Japan.
出版信息
Nature. 1989 Nov 2;342(6245):32-8. doi: 10.1038/342032a0.
DOI:10.1038/342032a0
PMID:2554142
Abstract
Cloning and expression of functional P400 protein from cerebellar Purkinje neurons shows that this protein is a receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium.
摘要
从小脑浦肯野神经元克隆并表达功能性P400蛋白，结果表明该蛋白是肌醇1,4,5 -三磷酸的受体，肌醇1,4,5 -三磷酸是一种介导细胞内钙释放的第二信使。
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