基于质谱的蛋白质组学方法用于发现HIV与宿主的相互作用。
Mass spectrometry-based proteomic approaches for discovery of HIV-host interactions.
作者信息
Luo Yang, Muesing Mark A
机构信息
Aaron Diamond AIDS Research Center, Affiliate of The Rockefeller University, 455 First Avenue 7th Floor, New York, NY 10016, USA.
出版信息
Future Virol. 2014;9(11):979-992. doi: 10.2217/fvl.14.86.
Abstract
A molecular understanding of viral infection requires a multi-disciplinary approach. Mass spectrometry has emerged as an indispensable tool to investigate the complex and dynamic interactions between HIV-1 and its host. It has been employed to study protein associations, changes in protein abundance and post-translational modifications occurring after viral infection. Here, we review and provide examples of mass spectrometry-based proteomic approaches currently used to explore virus-host interaction. Efforts in this area are certain to accelerate the discovery of the unique molecular strategies utilized by the virus to commandeer the cell as well as mechanisms of host defense.
摘要
对病毒感染的分子理解需要多学科方法。质谱已成为研究HIV-1与其宿主之间复杂动态相互作用不可或缺的工具。它已被用于研究病毒感染后发生的蛋白质关联、蛋白质丰度变化和翻译后修饰。在这里，我们回顾并举例说明目前用于探索病毒-宿主相互作用的基于质谱的蛋白质组学方法。该领域的努力必将加速发现病毒用来控制细胞的独特分子策略以及宿主防御机制。
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2
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3
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Mol Cell Proteomics. 2014 Jan;13(1):184-203. doi: 10.1074/mcp.M113.030155. Epub 2013 Oct 29.
4
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J Virol. 2013 Nov;87(21):11516-24. doi: 10.1128/JVI.01642-13. Epub 2013 Aug 21.
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