De Seta Daniele, Mancini Patrizia, Minni Antonio, Prosperini Luca, De Seta Elio, Attanasio Giuseppe, Covelli Edoardo, De Carlo Andrea, Filipo Roberto
Department of Sense Organs, Sapienza University of Rome, Policlinico Umberto I, Viale del Policlinico 155, 00161 Rome, Italy.
Department of Neurology, Sapienza University of Rome, Italy.
ScientificWorldJournal. 2014;2014:801971. doi: 10.1155/2014/801971. Epub 2014 Nov 27.
This individual prospective cohort study aims to report and analyze the symptoms preceding and accompanying the facial paresis in Bell's palsy (BP). Two hundred sixty-nine patients affected by BP with a maximum delay of 48 hours from the onset were enrolled in the study. The evolution of the facial paresis expressed as House-Brackmann grade in the first 10 days and its correlation with symptoms were analyzed. At the onset, 136 patients presented postauricular pain, 114 were affected by dry eye, and 94 reported dysgeusia. Dry mouth was present in 54 patients (19.7%), facial pain, hyperlacrimation, aural fullness, and hyperacusis represented a smaller percentage of the reported symptoms. After 10 days, 39.9% of the group had a severe paresis while 10.2% reached a complete recovery. Dry mouth at the onset was correlated with severe grade of palsy and was prognostic for poor recovery in the early period. These outcomes lead to the deduction that the nervus intermedius plays an important role in the presentation of the BP and it might be responsible for most of the accompanying symptomatology of the paresis. Our findings could be of important interest to early address a BP patient to further examinations and subsequent therapy.
这项个体前瞻性队列研究旨在报告和分析贝尔麻痹（BP）中面神经麻痹之前及伴随的症状。本研究纳入了269例BP患者，发病后最长延迟48小时。分析了前10天面神经麻痹以House-Brackmann分级表示的病情演变及其与症状的相关性。发病时，136例患者出现耳后疼痛，114例有干眼症状，94例报告有味觉障碍。54例患者（19.7%）有口干症状，面部疼痛、流泪过多、耳闷和听觉过敏在报告症状中所占比例较小。10天后，该组39.9%的患者出现严重麻痹，10.2%的患者完全恢复。发病时口干与麻痹的严重程度相关，且是早期恢复不良的预后指标。这些结果表明中间神经在BP的表现中起重要作用，可能是导致麻痹伴随的大多数症状的原因。我们的研究结果对于早期让BP患者接受进一步检查和后续治疗可能具有重要意义。
