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预测贝尔面瘫患者预后的临床预后指标:来自印度南部本地治里的一项描述性纵向研究。

Clinical Prognostic Indicators in Predicting the Outcome in Patients with Bell's Palsy: A Descriptive, longitudinal Study from Puducherry, South India.

作者信息

Amalanathan Sophia, Colbert Kumaran Ramesh, Kumar C Satish, Mathyalagen Prakash

机构信息

Department of ENT, Indira Gandhi Medical College & Research Institute, Vazhudavur Road, Kathirkamam, Puducherry, India.

Department of Community Health, Indira Gandhi Medical College & Research Institute, Vazhudavur Road, Kathirkamam, Puducherry, India.

出版信息

Indian J Otolaryngol Head Neck Surg. 2022 Dec;74(Suppl 3):4270-4275. doi: 10.1007/s12070-021-02935-9. Epub 2021 Oct 23.

DOI:10.1007/s12070-021-02935-9
PMID:36742483
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9895548/
Abstract

Electrophysiological studies can objectively predict the functional recovery in Bell's palsy but, the clinical prognostic indicators seem to be more practical where the nerve conduction studies are not available. To determine the clinical prognostic indicators in Bell's palsy patients and to determine the indicators with poor outcome for recovery. We designed a prospective, descriptive, and observational analysis of Bell's palsy patients, who presented to our ENT outpatients department. 34 patients with Bell's palsy were recruited for this study. We studied the demographic characteristics, sidedness, associated symptoms, time of presentation, grade, and therapeutic options. All the patients were followed up for 8 weeks and the final grade of functional recovery of the nerve was recorded. The patient information was entered in Epicollect 5software and the output was analysed as descriptive statistics. Hypothesis testing was accomplished by means of χ2 test or Fischer exact test, to compare the proportions of categorical data and continuous data using the Mann-Whitney U test. 91.17% (31/34) of Bell's palsy patients had complete facial nerve function recovery at the end of 8 weeks. Higher Age > 40 years ( = 0.022) and BP patients with coronary artery disease ( = 0.005) were the only two significant indicators for incomplete recovery. We suggest that all Bell's palsy patients seek medical advice early at the onset,especially the BP patients of older age and with coronary artery disease for faster recovery.

摘要

电生理研究可以客观地预测贝尔面瘫的功能恢复情况,但是,在无法进行神经传导研究的情况下,临床预后指标似乎更具实用性。为了确定贝尔面瘫患者的临床预后指标,并确定恢复结果较差的指标。我们对前来我院耳鼻喉科门诊的贝尔面瘫患者进行了一项前瞻性、描述性和观察性分析。本研究招募了34例贝尔面瘫患者。我们研究了人口统计学特征、患侧、相关症状、就诊时间、分级和治疗选择。所有患者均随访8周,并记录神经功能恢复的最终分级。将患者信息录入Epicollect 5软件,并将输出结果作为描述性统计数据进行分析。通过χ2检验或费舍尔精确检验进行假设检验,使用曼-惠特尼U检验比较分类数据和连续数据的比例。91.17%(31/34)的贝尔面瘫患者在8周结束时面神经功能完全恢复。年龄大于40岁(P = 0.022)和患有冠状动脉疾病的贝尔面瘫患者(P = 0.005)是不完全恢复的仅有的两个显著指标。我们建议所有贝尔面瘫患者在发病初期尽早寻求医疗建议,尤其是年龄较大且患有冠状动脉疾病的贝尔面瘫患者,以便更快恢复。

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本文引用的文献

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Prognostic factors for the outcome of Bells' palsy: A cohort register-based study.贝尔面瘫结局的预后因素:基于队列的注册研究。
Clin Otolaryngol. 2020 Sep;45(5):754-761. doi: 10.1111/coa.13571. Epub 2020 May 27.
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Bell's Palsy: A Prospective Study.贝尔氏面瘫:一项前瞻性研究。
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