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Microfluidic methods for non-viral gene delivery.

作者信息

Lai Wing-Fu

机构信息

Department of Mechanical Engineering, The University of Hong Kong, Hong Kong Special Administrative Region, China.

出版信息

Curr Gene Ther. 2015;15(1):55-63. doi: 10.2174/1566523214666141114213915.

DOI:10.2174/1566523214666141114213915
PMID:25545920
Abstract

Microfluidics is a compelling technology that shows considerable promise in applications ranging from gene expression profiling to cell-based assays. Owing to its capacity to enable generation of single droplets and multiple droplet arrays with precisely controlled composition and a narrow size distribution, recently microfluidics has been exploited for delivery of genes. This article provides an overview of recent advances in microfluidic gene delivery, and speculates the prospects for further research. The objectives of this article are to illustrate the potential roles played by microfluidics in gene delivery research, and to shed new light on strategies to enhance the efficiency of gene therapy.

摘要

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