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双侧炎性肌纤维母细胞瘤性乳突炎

Bilateral inflammatory myofibroblastic tumor mastoiditis.

作者信息

Rodgers Brian, Bhalla Vidur, Zhang Da, El Atrouni Wissam, Wang Fen, Sundararajan Jayashree, Lin James

机构信息

Department of Otolaryngology-Head and Neck Surgery, University of Kansas Hospital, Kansas City, Kansas.

Department of Pathology and Laboratory Medicine, University of Kansas Hospital, Kansas City, Kansas.

出版信息

Head Neck. 2015 Nov;37(11):E142-5. doi: 10.1002/hed.23978. Epub 2015 Jun 26.

Abstract

BACKGROUND

Inflammatory myoblastic tumors (IMTs) are rare, mesenchymal neoplasms most commonly located in areas of previous inflammation. In the temporal bone, these tumors typically present as solitary, space-occupying lesions that clinically resemble chronic otitis media.

METHODS

We present a case of bilateral IMTs with facial nerve involvement, sigmoid sinus thrombosis, leptomeningeal enhancement, and seizures.

RESULTS/CONCLUSION: This case demonstrates the need for a high index of suspicion of IMT when imaging reveals bilateral mastoid opacification. These tumors are more aggressive than their orbital counterparts and require multimodality therapy to prevent recurrence and alleviate severe neurotologic symptoms.

摘要

背景

炎性肌纤维母细胞瘤(IMTs)是罕见的间叶性肿瘤,最常位于既往有炎症的区域。在颞骨中,这些肿瘤通常表现为孤立的占位性病变,临床上类似于慢性中耳炎。

方法

我们报告一例双侧IMTs病例,伴有面神经受累、乙状窦血栓形成、软脑膜强化和癫痫发作。

结果/结论:该病例表明,当影像学显示双侧乳突混浊时,需要高度怀疑IMT。这些肿瘤比眼眶部位的同类肿瘤更具侵袭性,需要多模式治疗以预防复发并缓解严重的神经耳科症状。

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