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1例以慢性化脓性中耳炎为表现的乳突炎性肌纤维母细胞瘤。

A case of an inflammatory myofibroblastic tumor of the mastoid presenting with chronic suppurative otitis media.

作者信息

Cho Kwang-Jae, Lee Dong-Hee, Jung Sang-Hee, Kim Jung-Hyun

机构信息

Department of Otolaryngology-Head and Neck Surgery, College of Medicine, The Catholic University of Korea, 505 Banpo-dong, Secho-gu, Seoul 137-701, Republic of Korea.

出版信息

Auris Nasus Larynx. 2007 Dec;34(4):523-6. doi: 10.1016/j.anl.2007.03.005. Epub 2007 Apr 27.

Abstract

Inflammatory myofibroblastic tumors, also known as inflammatory pseudotumors, include a diverse group of lesions characterized by inflammatory cell infiltration and variable fibrotic responses. Their occurrence in the temporal bone is unusual. We present a case of an inflammatory myofibroblastic tumor of the mastoid bone in a 55-year-old female who complained of repeated otorrhea and a hearing impairment. On an otoscopic exam, her tympanic membrane was perforated. The computed tomographic imaging revealed a soft-tissue density-filled middle ear and mastoid with sclerotic bony change. The initial clinical diagnosis was chronic suppurative otitis media and mastoiditis, and the patient underwent a canal-wall down tympanomastoidectomy through a retroauricular approach. A histopathologic examination showed the presence of myofibroblastic spindle cells with mixed inflammatory infiltrates, and the pathologic diagnosis was inflammatory myofibroblastic tumor.

摘要

炎性肌纤维母细胞瘤,也称为炎性假瘤,包括一组以炎性细胞浸润和不同程度纤维化反应为特征的病变。它们在颞骨中发生较为罕见。我们报告一例55岁女性乳突骨炎性肌纤维母细胞瘤病例,该患者主诉反复耳漏和听力障碍。耳镜检查发现其鼓膜穿孔。计算机断层扫描成像显示中耳和乳突有软组织密度影并伴有骨质硬化改变。最初的临床诊断为慢性化脓性中耳炎和乳突炎,患者通过耳后入路接受了开放式鼓室乳突切除术。组织病理学检查显示存在肌纤维母细胞梭形细胞并伴有混合性炎性浸润,病理诊断为炎性肌纤维母细胞瘤。

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