Ohba Seigo, Yoshimura Hitoshi, Matsuda Shinpei, Imamura Yoshiaki, Sano Kazuo
Cranio. 2015 Jan;33(1):42-5. doi: 10.1179/0886963413Z.00000000026. Epub 2014 Jan 24.
Spindle cell carcinoma (SPCC) is a subtype of squamous cell carcinoma, and it mainly occurs in the upper aerodigestive duct. On the other hand, it rarely arises in the head and neck region. The prognosis of this tumor is usually poor because of its highly malignant behavior, such as its high incidence of recurrence or metastasis to cervical lymph nodes. However, the number of accumulated cases is still too low to provide the full details of SPCC.
The case of SPCC was counted by using database, PubMed. The authors also present a case of SPCC arising at the left buccal mucosa in a 72-year-old Japanese female in the current study.
Only six cases of SPCC arising at the buccal mucosa have been reported previously. The authors' patient died from a recurrent tumor 15 months after the first operation.
The authors have added this case to the previous knowledge of SPCC arising at the buccal mucosa, and discuss the clinical behavior of SPCC to help suggest a standard treatment strategy for the disease.
梭形细胞癌（SPCC）是鳞状细胞癌的一种亚型，主要发生于上呼吸消化道。另一方面，它很少发生于头颈部区域。由于其高度恶性行为，如高复发率或颈部淋巴结转移率，该肿瘤的预后通常较差。然而，累积病例数仍然过少，无法提供SPCC的全部细节。
通过使用数据库PubMed对SPCC病例进行计数。作者在本研究中还报告了一例发生于一名72岁日本女性左侧颊黏膜的SPCC病例。
此前仅报道过6例发生于颊黏膜的SPCC病例。作者的患者在首次手术后15个月死于复发性肿瘤。
作者将该病例补充到此前关于发生于颊黏膜的SPCC的知识中，并讨论了SPCC的临床行为，以帮助提出该病的标准治疗策略。
