Division of Cardiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Division of Cardiology, Cheju Halla General Hospital, Jeju, Korea.
Can J Cardiol. 2015 Jan;31(1):69-75. doi: 10.1016/j.cjca.2014.11.003. Epub 2014 Nov 6.
In some patients with severe tricuspid regurgitation (TR) who undergo tricuspid annuloplasty (TAP), significant remnant TR is detected early after TAP but diminishes after long-term follow-up. We sought to investigate the outcome of significant residual TR early after TAP and the predictors for late improvement of TR.
A total of 58 consecutive patients presenting with moderate to severe TR early (5.7 ± 2.0 days) after TAP and before discharge were enrolled in this study. Echocardiography was repeated for 32.3 ± 28.6 months after TAP, and improvements in TR were defined as mild or less TR. Clinical data and echocardiographic studies were retrospectively analyzed.
Twenty-nine (50%) patients showed late improvement in TR during follow-up. Multivariate Cox regression analysis revealed that tricuspid valve (TV) tenting height measured early after TAP (P = 0.020) and execution of the Maze procedure with TAP (P = 0.049) were independent predictors for late improvement of significant early remnant TR. The rates of late TR improvement were higher in patients with an early postoperative TV tenting height ≥ 9.1 mm (P = 0.026) and in patients who underwent a Maze procedure (P = 0.033) than in other groups of patients.
Half of patients with significant remnant TR early after TAP show late improvement in TR. Evaluation of a combined Maze procedure and TV tenting height early after TAP will help identify patients for whom repeated TV surgery may be deferred.
在一些接受三尖瓣环成形术(TAP)的重度三尖瓣反流(TR)患者中,TAP 后早期会检测到明显的残余 TR,但在长期随访后会减轻。我们试图研究 TAP 后早期出现明显残余 TR 的结果,以及预测 TR 晚期改善的因素。
本研究共纳入 58 例 TAP 后早期(5.7±2.0 天)且在出院前出现中重度 TR 的连续患者。TAP 后 32.3±28.6 个月进行重复超声心动图检查,TR 改善定义为轻度或更轻的 TR。回顾性分析临床数据和超声心动图研究。
29 例(50%)患者在随访期间出现晚期 TR 改善。多变量 Cox 回归分析显示,TAP 后早期测量的三尖瓣(TV)瓣叶膨出高度(P=0.020)和 TAP 联合迷宫手术(P=0.049)是晚期显著残余 TR 改善的独立预测因素。术后 TV 瓣叶膨出高度≥9.1mm(P=0.026)和接受迷宫手术的患者(P=0.033)晚期 TR 改善率高于其他患者组。
TAP 后早期出现明显残余 TR 的患者中有一半会出现晚期 TR 改善。评估 TAP 后早期的联合迷宫手术和 TV 瓣叶膨出高度有助于识别可能延迟再次 TV 手术的患者。