Cedars-Sinai Heart Institute, Cedars-Sinai Medical Center, 127 South San Vicente Boulevard A3411, Los Angeles, CA 90048, USA.
Eur Heart J Cardiovasc Imaging. 2017 Jul 1;18(7):809-817. doi: 10.1093/ehjci/jew323.
Tricuspid valve (TV) annuloplasty is an effective treatment for tricuspid regurgitation (TR). However, the impact of TV morphology on outcome of TV annuloplasty remains unknown. We sought to investigate the relationship between preoperative TV morphology and residual TR after annuloplasty.
Two-dimensional transthoracic and three-dimensional (3D) transesophageal echocardiography were performed in 97 patients with functional TR before and after surgery. 3D quantitative assessment including annular dimension, tenting height and volume, and lengths and tethering angles of the 3 leaflets was performed. The TV morphological score was derived from the preoperative 3D echocardiography to score a leaflet mobility, leaflet thickening, subvalvular thickening, and calcification. TR severity was determined by the averaged vena contracta measured from the apical and parasternal inflow views. Multivariable analysis revealed that a shorter total leaflet length (P = 0.007), larger tenting volume (P < 0.001), and higher TV morphological score (P < 0.001) were independently associated with residual TR. A TV-Echo score was determined as a sum of points based on receiver operator characteristics analysis: total leaflet length >61.0 mm, 61.0 to 53.5 mm, and <53.5 mm; tenting volume <2.3 mL, 2.3 to 3.5 mL, and >3.5 mL; and TV morphological score <7, 7 to 18, and >18; each variable was associated with 0 and 1 point and 2 points, respectively. The TV-Echo score ≥2 was associated with significant residual TR with a sensitivity of 85.7% and a specificity of 71.0%.
In addition to tethering and short length of the leaflets, TV morphological abnormality predicted residual TR after TV annuloplasty.
三尖瓣瓣环成形术是治疗三尖瓣反流(TR)的有效方法。然而,三尖瓣形态对瓣环成形术结果的影响尚不清楚。我们旨在研究术前三尖瓣形态与瓣环成形术后残余 TR 的关系。
97 例功能性 TR 患者术前和术后均进行二维经胸和三维(3D)经食管超声心动图检查。进行了包括瓣环直径、瓣叶膨出高度和容积以及 3 个瓣叶长度和牵拉力角度在内的 3D 定量评估。基于术前 3D 超声心动图获得的三尖瓣形态评分用于评估瓣叶活动度、瓣叶增厚、瓣下增厚和钙化。TR 严重程度通过心尖和胸骨旁流入道的平均收缩期瓣口宽度确定。多变量分析显示,总瓣叶长度较短(P=0.007)、膨出容积较大(P<0.001)和三尖瓣形态评分较高(P<0.001)与残余 TR 独立相关。根据受试者工作特征曲线分析确定了三尖瓣超声心动图评分(TV-Echo 评分):总瓣叶长度>61.0mm、61.0 至 53.5mm 和<53.5mm;膨出容积<2.3mL、2.3 至 3.5mL 和>3.5mL;以及三尖瓣形态评分<7、7 至 18 和>18;每个变量分别与 0 分、1 分和 2 分相关。TV-Echo 评分≥2 与显著残余 TR 相关,敏感性为 85.7%,特异性为 71.0%。
除了瓣叶的牵拉力和缩短外,三尖瓣形态异常也可预测三尖瓣瓣环成形术后残余 TR。