Hammoud S, Tissier A-M, Elie C, Pousset M, Knebelman B, Joly D, Hélénon O, Correas J-M
Service de radiologie adulte, hôpital Necker-Enfants-malades, 149, rue de Sèvres, 75015 Paris, France.
Service de biostatistique, hôpital Necker-Enfants-malades, 149, rue de Sèvres, 75015 Paris, France; Université Paris Descartes Sorbonne Paris Cité, Paris, France.
Diagn Interv Imaging. 2015 Jan;96(1):65-71. doi: 10.1016/j.diii.2013.04.002. Epub 2014 Dec 23.
To investigate the correlation and concordance between the ellipsoid volume calculated by ultrasonography measurements (Vol3DUS) and the reference kidney volume measured by CT (VolTDM) in early autosomal dominant polycystic kidney disease (ADPKD).
Prospective study of the correlation and concordance of renal volumes in 24 patients with early ADPKD (48 kidneys analysed separately), with calculation of Vol3DUS using the formula for an ellipsoid in three different manners and VolTDM measurement by manual contouring. Calculations of correlation coefficients (r) and coefficients of intra-class correlation (ICC) with confidence intervals at 95%.
The US volume was strongly correlated with the CT volume by using the maximum width in a transverse section (r=0.83) with a mean Vol3DUS=692±348ml [180; 2069]. The most reproducible ultrasonography measurement was the height. When the kidney volume exceeded 800ml, US underestimated the volume. However, the median error was -57.5ml [-1090; 183] and 85% of the Vol3DUS calculated differed by more than 5% from the reference measurement.
The correlation between the US calculated volumes and the CT volumes was strong. However, the median error with ellipsoid US volume was too high to detect a small renal variation in early ADPKD.
研究超声测量计算的椭球体体积（Vol3DUS）与计算机断层扫描（CT）测量的参考肾体积（VolTDM）在常染色体显性遗传性多囊肾病（ADPKD）早期阶段的相关性和一致性。
对24例ADPKD早期患者（分别分析48个肾脏）的肾体积相关性和一致性进行前瞻性研究，采用三种不同方式使用椭球体公式计算Vol3DUS，并通过手动勾勒轮廓测量VolTDM。计算相关系数（r）和组内相关系数（ICC）以及95%置信区间。
通过使用横断面最大宽度，超声体积与CT体积高度相关（r = 0.83），平均Vol3DUS = 692±348ml[180；2069]。超声测量中最具可重复性的是高度。当肾体积超过800ml时，超声会低估体积。然而，中位数误差为 - 57.5ml[-1090；183]，并且计算出的Vol3DUS中有85%与参考测量值相差超过5%。
超声计算体积与CT体积之间相关性很强。然而，椭球体超声体积的中位数误差过高，无法检测出ADPKD早期阶段肾脏的微小变化。
