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乳腺巨大恶性叶状肿瘤

Giant malignant phyllodes tumour of breast.

作者信息

Krishnamoorthy Ramakrishnan, Savasere Thejas, Prabhuswamy Vinod Kumar, Babu Rajashekhara, Shivaswamy Sadashivaiah

机构信息

Department of General Surgery, Victoria Hospital, Bangalore Medical College and Research Institute, Bangalore, India.

出版信息

Case Rep Oncol Med. 2014;2014:956856. doi: 10.1155/2014/956856. Epub 2014 Dec 4.

Abstract

The term phyllodes tumour includes lesions ranging from completely benign tumours to malignant sarcomas. Clinically phyllodes tumours are smooth, rounded, and usually painless multinodular lesions indistinguishable from fibroadenomas. Percentage of phyllodes tumour classified as malignant ranges from 23% to 50%. We report a case of second largest phyllodes tumour in a 35-year-old lady who presented with swelling of right breast since 6 months, initially small in size, that progressed gradually to present size. Examination revealed mass in the right breast measuring 36×32 cms with lobulated firm surface and weighing 10 kgs. Fine needle aspiration cytology was reported as borderline phyllodes; however core biopsy examination showed biphasic neoplasm with malignant stromal component. Simple mastectomy was done and specimen was sent for histopathological examination which confirmed the core biopsy report. Postoperatively the patient received chemotherapy and radiotherapy. The patient is on follow-up for a year and has not shown any evidence of metastasis or recurrence.

摘要

叶状肿瘤这一术语涵盖了从完全良性肿瘤到恶性肉瘤的一系列病变。临床上,叶状肿瘤表现为光滑、圆形且通常无痛的多结节性病变,与纤维腺瘤难以区分。被归类为恶性的叶状肿瘤比例在23%至50%之间。我们报告一例35岁女性的第二大叶状肿瘤病例,该患者自6个月前起出现右乳肿胀,起初肿块较小,随后逐渐发展至当前大小。检查发现右乳有一肿块,大小为36×32厘米,表面呈分叶状且质地坚硬,重达10千克。细针穿刺细胞学检查报告为临界性叶状肿瘤;然而,粗针活检检查显示为具有恶性间质成分的双相性肿瘤。实施了单纯乳房切除术,并将标本送去进行组织病理学检查,结果证实了粗针活检报告。术后患者接受了化疗和放疗。该患者已接受一年的随访,未显示任何转移或复发迹象。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e07/4273467/bbf854e5e302/CRIONM2014-956856.001.jpg

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