Hirota Kazunari, Itoh Yuji, Rii Tosho, Inoue Makoto, Hirakata Akito
*Kyorin Eye Center, Kyorin University School of Medicine, Tokyo, Japan; and †Department of Ophthalmology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan.
Retina. 2015 May;35(5):908-14. doi: 10.1097/IAE.0000000000000414.
To determine the correlation between the integrity of the foveal microstructures and the best-corrected visual acuity (BCVA) after pars plana vitrectomy for a macular pseudohole.
Thirty-one eyes of 31 patients with a macular pseudohole underwent vitrectomy with internal limiting membrane removal. The foveal area was examined by spectral domain optical coherence tomography preoperatively and postoperatively. The correlations between the BCVA and the lengths of the photoreceptor interdigitation zone (IZ), the ellipsoid zone, and the external limiting membrane band defects, and central foveal thickness were determined.
The BCVA improved significantly and the length of the IZ band defect decreased significantly after the surgery. Simple linear regression analyses showed that the BCVA was significantly correlated with the length of the IZ band defect preoperatively and also at 1 to 12 months postoperatively (P < 0.001 for all). The BCVA was not significantly correlated with the length of the ellipsoid zone, external limiting membrane band defect, and the central foveal thickness.
The significant correlation between the length of the foveal IZ band defect and the BCVA preoperatively and postoperatively indicates that the foveal IZ band is related to the visual recovery in patients with macular pseudohole.
确定黄斑假孔行玻璃体切割术后黄斑微结构完整性与最佳矫正视力（BCVA）之间的相关性。
31例黄斑假孔患者的31只眼接受了玻璃体切割联合内界膜剥除术。术前和术后通过光谱域光学相干断层扫描检查黄斑区。确定BCVA与光感受器指状交叉区（IZ）、椭圆体区长度、外界膜带缺损以及中心凹厚度之间的相关性。
术后BCVA显著提高，IZ带缺损长度显著缩短。简单线性回归分析显示，术前及术后1至12个月BCVA与IZ带缺损长度均显著相关（均P < 0.001）。BCVA与椭圆体区长度、外界膜带缺损及中心凹厚度无显著相关性。
术前和术后黄斑IZ带缺损长度与BCVA显著相关，表明黄斑IZ带与黄斑假孔患者的视力恢复有关。
