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手术室甲醛暴露后发生的鼻窦腺样囊性癌。

Sinonasal adenoid cystic carcinoma following formaldehyde exposure in the operating theatre.

机构信息

Department of Environmental and Occupational Medicine, Oslo University Hospital, PO Box 4956, Nydalen, Oslo, NO-0424 Norway.

Department of Pathology, Vestfold Hospital Trust, Tønsberg, Norway.

出版信息

J Occup Med Toxicol. 2014 Dec 17;9(1):43. doi: 10.1186/s12995-014-0043-4. eCollection 2014.

DOI:10.1186/s12995-014-0043-4
PMID:25550707
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4279905/
Abstract

We present a case report of an auxiliary nurse who developed an adenoid cystic carcinoma in her left maxillary sinus following occupational exposure to formaldehyde in the operating theatre. Currently, the epidemiological evidence that formaldehyde can cause cancer in humans is considered to be limited. Previous case-control-studies of formaldehyde and sinonasal cancer have mainly investigated subjects who were concomitantly exposed to wood dust, a known risk factor to the development of sinonasal adenocarcinoma of intestinal type. Our case report presents a patient who has developed an adenoid cystic carcinoma following exposure to formaldehyde. We suggest that the occupational physician remains alert to formaldehyde as an occupational hazard among health care workers.

摘要

我们报告了一例左上颌窦腺样囊性癌病例,该患者是一名手术室辅助护士,职业性接触甲醛。目前,认为甲醛可致癌的流行病学证据有限。既往关于甲醛和鼻腔鼻窦癌的病例对照研究主要调查了同时接触已知的鼻腔肠型腺癌发病危险因素-木屑的人群。我们的病例报告介绍了一名在接触甲醛后发生腺样囊性癌的患者。我们建议职业医生对医护人员职业性接触甲醛的危害保持警惕。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b532/4279905/5a56b90b5492/12995_2014_43_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b532/4279905/5a56b90b5492/12995_2014_43_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b532/4279905/5a56b90b5492/12995_2014_43_Fig1_HTML.jpg

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本文引用的文献

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Int J Oral Maxillofac Surg. 2014 Nov;43(11):1313-8. doi: 10.1016/j.ijom.2014.06.016. Epub 2014 Jul 31.
2
Adenoid cystic carcinoma of the nasal cavity and paranasal sinuses: a meta-analysis.鼻腔和鼻窦腺样囊性癌:一项荟萃分析
J Neurol Surg B Skull Base. 2013 Jun;74(3):118-25. doi: 10.1055/s-0033-1347358. Epub 2013 May 15.
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Primary Sjogren's syndrome and malignancy risk: a systematic review and meta-analysis.
观赏植物对室内环境中甲醛的植物修复:一种促进居住者健康的方法。
Int J Prev Med. 2018 Aug 14;9:70. doi: 10.4103/ijpvm.IJPVM_269_16. eCollection 2018.
原发性干燥综合征与恶性肿瘤风险:系统评价和荟萃分析。
Ann Rheum Dis. 2014 Jun;73(6):1151-6. doi: 10.1136/annrheumdis-2013-203305. Epub 2013 May 17.
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Sinonasal adenoid cystic carcinoma: comprehensive analysis of incidence and survival from 1973 to 2009.鼻腔鼻窦腺样囊性癌:1973 年至 2009 年发病率和生存情况的综合分析。
Laryngoscope. 2013 Jul;123(7):1592-7. doi: 10.1002/lary.24085. Epub 2013 Apr 1.
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Personal habits and indoor combustions.个人习惯与室内燃烧
IARC Monogr Eval Carcinog Risks Hum. 2012;100(Pt E):1-538.
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Chemical agents and related occupations.化学制剂及相关职业。
IARC Monogr Eval Carcinog Risks Hum. 2012;100(Pt F):9-562.
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Imaging of sinonasal tumours.鼻窦肿瘤的影像学表现。
Cancer Imaging. 2012 May 7;12:136-52. doi: 10.1102/1470-7330.2012.0015.
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Association between cleaning-related chemicals and work-related asthma and asthma symptoms among healthcare professionals.医护人员中与清洁相关的化学物质与职业性哮喘及哮喘症状之间的关联。
Occup Environ Med. 2012 Jan;69(1):35-40. doi: 10.1136/oem.2011.064865. Epub 2011 May 20.
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Arch Pathol Lab Med. 2011 Apr;135(4):511-5. doi: 10.5858/2009-0527-RS.1.
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