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结肠复合型B细胞淋巴瘤累及肠系淋巴结并合并腺癌及血吸虫感染:一例报告

Colon composited B cell lymphoma involving intestinal mesenteric lymph nodes combined with adenocarcinoma and schistosome infection: a case report.

作者信息

Xiong Hanzhen, Chen Juan, Liu Shaoyan, Chen Hui, Jiang Qingping

机构信息

Department of Pathology, The Third Affiliated Hospital, Guangzhou Medical University.

出版信息

Int J Clin Exp Pathol. 2014 Oct 15;7(11):8159-62. eCollection 2014.

Abstract

Here we reported one rare case of colon composited B cell lymphoma associated with adenocarcinoma. The composited B cell lymphoma composed of extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) and large B-cell lymphoma. Additionally, adjacent intestinal mesenteric lymph modes were involved. And interestingly, schistosome infection was also found in lymphoma and adjacent tissues. The patient was given a usual local intestinal resection for colon adenocarcinoma. But in the site of one surgical margin, 10 cm away from intestinal carcinoma, we found another mass. Beneath the neoplasm, several swollen intestinal mesenteric lymph nodes were detected. By H&E staining and immunohistochemistry, it was eventually demonstrated the patient suffered complicated neoplasms. So far, there were just several references about colon lymphoma combined with adenocarcinoma. But the present case is the first to report that colon composited B cell lymphoma associated with adenocarcinoma and schistosome infection.

摘要

在此,我们报告了一例罕见的结肠复合型B细胞淋巴瘤合并腺癌的病例。该复合型B细胞淋巴瘤由黏膜相关淋巴组织结外边缘区B细胞淋巴瘤(MALT淋巴瘤)和大B细胞淋巴瘤组成。此外,相邻的肠系膜淋巴结也受到累及。有趣的是,在淋巴瘤及相邻组织中还发现了血吸虫感染。该患者因结肠腺癌接受了常规的局部肠切除术。但在距肠癌10厘米的一个手术切缘处,我们发现了另一个肿物。在该肿瘤下方,检测到几个肿大的肠系膜淋巴结。通过苏木精-伊红(H&E)染色和免疫组化,最终证实该患者患有复杂的肿瘤。到目前为止,关于结肠淋巴瘤合并腺癌的参考文献仅有几篇。但本病例是首例报道的结肠复合型B细胞淋巴瘤合并腺癌及血吸虫感染的病例。

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