Hardman W J, Gal A A, Pascal R R
Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Ga 30322, USA.
South Med J. 1997 Apr;90(4):426-30. doi: 10.1097/00007611-199704000-00014.
We describe the synchronous occurrence of gastric signet-ring cell adenocarcinoma and low-grade B-cell lymphoma of mucosa-associated lymphoid tissue in a patient with chronic gastritis and intestinal metaplasia. Histologic features of the mucosal inflammation, a follicular gastritis, were suggestive of a chronic Helicobacter pylori infection. Previous hypotheses concerning the relationship of long-standing gastritis and development of gastric carcinoma and lymphoma are supported by our findings.
我们描述了一名患有慢性胃炎和肠化生的患者同时发生胃印戒细胞腺癌和黏膜相关淋巴组织低度B细胞淋巴瘤的情况。黏膜炎症（滤泡性胃炎）的组织学特征提示存在慢性幽门螺杆菌感染。我们的研究结果支持了先前关于长期胃炎与胃癌和淋巴瘤发生关系的假说。
