Hu Yue-Ming, Yan Ji-Dong, Gao Yang, Xia Qing-An, Wu Yu, Zhang Zhi-Yong
Department of Pathology, Tangshan Gongren Hospital Tangshan, China.
Department of Thoracic Surgery, Tangshan Gongren Hospital Tangshan, China.
Int J Clin Exp Pathol. 2014 Oct 15;7(11):8176-80. eCollection 2014.
Primary malignant melanoma of esophagus is a rare but highly aggressive neoplasm, with an incidence less than 0.2% of all primary esophagus neoplasms. There are no clinical differences from other forms of esophagus cancer. Because initial symptoms are nonspecific, the patients are usually diagnosed at a late stage. The prognosis is poor, and curative effect seems disappointed. Several reports suggest that most of patients die from distant metastases, and the 5-year survival rate is approximately 4.2%. This case report includes a review of the surgical pathology, clinical features and treatment of primary malignant melanoma of esophagus. This case report presents a 56-year-old female with primary malignant melanoma of esophagus, treated by surgical resection. Till now, the patient is still alive for 5 months without any chemotherapy, radiotherapy and immunomodulatory therapy.
原发性食管恶性黑色素瘤是一种罕见但侵袭性很强的肿瘤，在所有原发性食管肿瘤中的发病率不到0.2%。它与其他形式的食管癌在临床症状上并无差异。由于初始症状不具有特异性，患者通常在晚期才被诊断出来。其预后较差，治疗效果似乎令人失望。多项报告表明，大多数患者死于远处转移，5年生存率约为4.2%。本病例报告包括对原发性食管恶性黑色素瘤的手术病理、临床特征及治疗的回顾。本病例报告介绍了一名56岁患有原发性食管恶性黑色素瘤的女性患者，经手术切除治疗。截至目前，该患者未经任何化疗、放疗及免疫调节治疗，已存活5个月。
