一名绝经后女性患有双侧卵巢混合性上皮腺癌，伴有单侧卵巢卵黄囊瘤成分。
Bilateral ovarian mixed epithelial adenocarcinoma in a postmenopausal woman with unilateral ovarian yolk sac tumor component.
作者信息
Chen Qin, Chen Xiaoduan
机构信息
Department of Pathology, Women's Hospital, School of Medicine, Zhejiang University.
出版信息
Int J Clin Exp Pathol. 2014 Oct 15;7(11):8259-65. eCollection 2014.
Abstract
Ovarian yolk sac tumors (YSTs) usually occur in the young women and have been rarely documented in perimenopausal and postmenopausal women. The different age distribution supposes their complex nomenclature and histogenesis. We report a case of bilateral ovarian epithelial carcinoma with right ovarian YST component in a postmenopausal woman. The patient was treated by surgery and adjuvant combination chemotherapy of taxol and carboplatin for 6 courses and has been clinically free of tumor for 6 months. The correlation between the YST and the epithelial components always confuse us. Ovarian yolk sac tumors are not a discrete entity and represent a multifaceted group of neoplasms. The conjunction of multi antibodies help in differential diagnoses. In addition to a thorough case description, the literature concerning this entity is reviewed and discussed.
摘要
卵巢卵黄囊瘤（YSTs）通常发生于年轻女性，在围绝经期和绝经后女性中鲜有报道。不同的年龄分布表明其命名和组织发生较为复杂。我们报告一例绝经后女性双侧卵巢上皮癌，右侧卵巢含有卵黄囊瘤成分。该患者接受了手术及紫杉醇和卡铂辅助联合化疗6个疗程，目前临床无瘤状态已达6个月。卵黄囊瘤与上皮成分之间的关系一直让我们感到困惑。卵巢卵黄囊瘤并非一个独立的实体，而是一组具有多面性的肿瘤。多种抗体联合有助于鉴别诊断。除了详细的病例描述外，还对有关该实体的文献进行了回顾和讨论。
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