Gökahmetoğlu Selma, Ferahbaş Ayten, Canöz Özlem
Erciyes University Medical Faculty Department of Microbiology; Erciyes University Medical Faculty Department of Dermatology; Erciyes University Medical Faculty Department of Pathology, Kayseri,Turkey.
Infez Med. 2014 Dec;22(4):322-5.
Focal epithelial hyperplasia (FEH) is a benign proliferative condition that is more frequently found in children of certain ethnic groups. Human papillomavirus (HPV) 13 and 32 genotypes has been consistently detected in these lesions. In this study a daughter, mother and father had FEH, and HPV 13 was shown by sequence analysis in the lesions of these patients. Cryotherapy was applied to the lesions and the lesions improved, but did not recover properly. In conclusion, HPV genotyping should be performed in FEH cases.
局灶性上皮增生（FEH）是一种良性增殖性疾病，在某些种族的儿童中更为常见。在这些病变中一直检测到人类乳头瘤病毒（HPV）13型和32型基因型。在本研究中，一名女儿、母亲和父亲患有FEH，通过序列分析在这些患者的病变中显示出HPV 13。对病变进行了冷冻治疗，病变有所改善，但未完全恢复。总之，FEH病例应进行HPV基因分型。
