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多形性胶质母细胞瘤伴少突胶质细胞和肉瘤成分的术中诊断

Intraoperative diagnosis of glioblastomamultiforme with oligodendroglial and sarcomatous components.

作者信息

Adlekha Shashikant, Chadha Tandra, Ragunath A, Sumangala B, George Robin

机构信息

Department of Pathology, Sree Narayana Institute of Medical Sciences, Ernakulam, Kerala, India.

Department of Microbiology, Sree Narayana Institute of Medical Sciences, Ernakulam, Kerala, India.

出版信息

J Neurosci Rural Pract. 2015 Jan;6(1):81-3. doi: 10.4103/0976-3147.143207.

Abstract

Glioblastoma, the most frequent primary brain tumor and the most malignant neoplasm, can have the most heterogeneous morphological presentation. Along with classical morphological features, areas of oligodendroglial component and mesenchymal differentiation may be seen. The present case was a rare case of glioblastoma presenting with sarcomatous and oligodendroglial components. The case was diagnosed intraoperatively by squash and touch cytology and later on confirmed by histopathological study.

摘要

胶质母细胞瘤是最常见的原发性脑肿瘤和最恶性的肿瘤,其形态表现可能最为异质性。除了经典的形态特征外,还可见少突胶质细胞成分和间充质分化区域。本病例是一例罕见的伴有肉瘤样和少突胶质细胞成分的胶质母细胞瘤。该病例通过压片和触摸细胞学在术中诊断,随后经组织病理学研究证实。

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