Adamson B D, Coughlan N J A, Markworth P B, Continetti R E, Bieske E J
School of Chemistry, The University of Melbourne, Victoria 3010, Australia.
Department of Chemistry and Biochemistry, University of California San Diego, 9500 Gilman Drive, La Jolla, California 92093-0340, USA.
Rev Sci Instrum. 2014 Dec;85(12):123109. doi: 10.1063/1.4903753.
An ion mobility mass spectrometry apparatus for investigating the photoisomerization and photodissociation of electrosprayed molecular ions in the gas phase is described. The device consists of a drift tube mobility spectrometer, with access for a laser beam that intercepts the drifting ion packet either coaxially or transversely, followed by a quadrupole mass filter. An ion gate halfway along the drift region allows the instrument to be used as a tandem ion mobility spectrometer, enabling mobility selection of ions prior to irradiation, with the photoisomer ions being separated over the second half of the drift tube. The utility of the device is illustrated with photoisomerization and photodissociation action spectra of carbocyanine molecular cations. The mobility resolution of the device for singly charged ions is typically 80 and it has a mass range of 100-440 Da, with the lower limit determined by the drive frequency for the ion funnels, and the upper limit by the quadrupole mass filter.
描述了一种用于研究气相中电喷雾分子离子的光异构化和光解离的离子迁移率质谱仪。该装置由一个漂移管迁移率光谱仪组成，有一个激光束通道，该激光束可同轴或横向拦截漂移的离子包，随后是一个四极质量过滤器。沿漂移区域中途的一个离子门使该仪器能够用作串联离子迁移率光谱仪，从而在辐照之前对离子进行迁移率选择，光异构离子在漂移管的后半部分被分离。用碳菁分子阳离子的光异构化和光解离作用光谱说明了该装置的效用。该装置对单电荷离子的迁移率分辨率通常为80，质量范围为100 - 440 Da，下限由离子漏斗的驱动频率决定，上限由四极质量过滤器决定。
