Koloverou Efi, Tentolouris Nikolaos, Bakoula Chryssa, Darviri Christina, Chrousos George
Hormones (Athens). 2014 Oct-Dec;13(4):509-18. doi: 10.14310/horm.2002.1492.
Although there is scientific evidence that stress adversely affects metabolic control, only a few studies have examined the role of stress management in improving glycemic control in patients with type 2 diabetes mellitus (DM). In this study, we investigated the effect of a relaxation technique on levels of stress and glycemic control.
A total of 53 patients with type 2 DM were randomly assigned to undergo either an 8-week stress management program, consisting of 10 min of diaphragmatic breathing and 15 min of progressive muscle relaxation twice per day (n=25, intervention group), or not (n=28, control group). Perceived stress, health locus of control and HbA1c were primary outcomes and were measured before and after intervention.
In the intervention group, perceived stress score (PSS) and HbA1c had decreased significantly (P<0.05) by the end of the program. Specifically concerning the PSS, the higher the initial levels of perceived stress the greater the benefit of the intervention. No other significant changes were found.
Our results show a beneficial role of stress management for patients with type 2 DM, as regards both stress levels and glycemic control. It is recommended to consider this type of treatment as an adjunct to conventional therapy. We deem that our study could encourage future studies in this area with larger samples, longer duration and more objective measurements.
尽管有科学证据表明压力会对代谢控制产生不利影响，但仅有少数研究探讨了压力管理在改善2型糖尿病（DM）患者血糖控制方面的作用。在本研究中，我们调查了一种放松技巧对压力水平和血糖控制的影响。
总共53例2型糖尿病患者被随机分配，一组接受为期8周的压力管理计划，包括每天两次10分钟的腹式呼吸和15分钟的渐进性肌肉放松（n = 25，干预组），另一组不接受（n = 28，对照组）。感知压力、健康控制点和糖化血红蛋白（HbA1c）是主要观察指标，在干预前后进行测量。
在干预组中，到计划结束时，感知压力评分（PSS）和HbA1c显著降低（P < 0.05）。具体而言，关于PSS，初始感知压力水平越高，干预的益处越大。未发现其他显著变化。
我们的结果表明，压力管理对2型糖尿病患者在压力水平和血糖控制方面均具有有益作用。建议将这种治疗方法视为传统治疗的辅助手段。我们认为我们的研究可以鼓励未来在该领域开展更大样本、更长疗程和更客观测量的研究。
