Valverde Israel, Gomez Gorka, Coserria Jose Felix, Suarez-Mejias Cristina, Uribe Sergio, Sotelo Julio, Velasco Maria Nieves, Santos De Soto Jose, Hosseinpour Amir-Reza, Gomez-Cia Tomas
Paediatric Cardiology Unit, Hospital Virgen Del Rocio, Seville, Spain; Cardiovascular Pathology Unit, Institute of Biomedicine of Seville, IBIS, Hospital Virgen De Rocio/CSIC/University of Seville, Seville, Spain.
Catheter Cardiovasc Interv. 2015 May;85(6):1006-12. doi: 10.1002/ccd.25810. Epub 2015 Feb 12.
To evaluate whether three-dimensional (3D) printed models can be used to improve interventional simulation and planning in patients with aortic arch hypoplasia.
Stenting of a hypoplastic transverse arch is technically challenging, and complications such as stent migration and partial obstruction of the origin of the head and neck vessels are highly dependent on operator skills and expertise.
Using magnetic resonance imaging (MRI) data, a 3D model of a repaired aortic coarctation of a 15-year-old boy with hypoplastic aortic arch was printed. Simulation of the endovascular stenting of the hypoplastic arch was carried out under fluoroscopic guidance in the 3D printed model, and subsequently in the patient. A Bland-Altman analysis was used to evaluate the agreement between measurements of aortic diameter in the 3D printed model and the patient's MRI and X-ray angiography.
The 3D printed model proved to be radio-opaque and allowed simulation of the stenting intervention. The assessment of optimal stent position, size, and length was found to be useful for the actual intervention in the patient. There was excellent agreement between the 3D printed model and both MRI and X-ray angiographic images (mean bias and standard deviation of 0.36 ± 0.45 mm).
3D printed models accurately replicate patients' anatomy and are helpful in planning endovascular stenting in transverse arch hypoplasia. This opens a door for potential simulation applications of 3D models in the field of catheterization and cardiovascular interventions.
评估三维(3D)打印模型是否可用于改善主动脉弓发育不全患者的介入模拟和规划。
对发育不全的横弓进行支架置入术在技术上具有挑战性,支架迁移和头颈部血管起始部部分阻塞等并发症高度依赖于操作者的技能和专业知识。
利用磁共振成像(MRI)数据,打印出一名患有主动脉弓发育不全的15岁男孩修复后主动脉缩窄的3D模型。在3D打印模型中,在荧光透视引导下模拟发育不全弓的血管内支架置入术,随后在患者体内进行。采用Bland-Altman分析评估3D打印模型中主动脉直径测量值与患者MRI及X线血管造影测量值之间的一致性。
3D打印模型被证明具有放射性不透明性,并允许模拟支架置入干预。发现对最佳支架位置、尺寸和长度的评估对患者的实际干预有用。3D打印模型与MRI及X线血管造影图像之间具有极好的一致性(平均偏差和标准差为0.36±0.45mm)。
3D打印模型能准确复制患者的解剖结构,有助于规划横弓发育不全的血管内支架置入术。这为3D模型在导管插入术和心血管介入领域的潜在模拟应用打开了一扇门。