Yoon Syn-Hae, Bang Ji-Yeon, Seo Hyungseok, Song Jun-Gol
Department of Anesthesiology and Pain Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Korean J Anesthesiol. 2014 Dec;67(6):412-5. doi: 10.4097/kjae.2014.67.6.412. Epub 2014 Dec 29.
Kounis syndrome is an acute coronary syndrome concurrently occurs with allergic or hypersensitivity reactions. In patient with this syndrome, inflammatory mediators released due to an allergic reaction implicate to induce coronary artery spasm and atheromatous plaque rupture. We describe a patient with coronary artery disease who developed acute perioperative myocardial infarction leading to cardiac arrest after the anaphylactic reaction to cisatracurium, which led to a suspicion of Kounis syndrome. Anesthesiologists should be aware that anaphylaxis or allergic reactions can progress to acute coronary syndrome, thereby significantly change the course of the disease.
库尼斯综合征是一种与过敏或超敏反应同时发生的急性冠状动脉综合征。在患有该综合征的患者中，过敏反应释放的炎症介质会引发冠状动脉痉挛和动脉粥样斑块破裂。我们描述了一名冠心病患者，在对顺式阿曲库铵发生过敏反应后出现围手术期急性心肌梗死，导致心脏骤停，这引发了对库尼斯综合征的怀疑。麻醉医生应意识到过敏反应或过敏可能进展为急性冠状动脉综合征，从而显著改变疾病进程。
