Tanaka Shinji, Saitoh Yusuke, Matsuda Takahisa, Igarashi Masahiro, Matsumoto Takayuki, Iwao Yasushi, Suzuki Yasumoto, Nishida Hiroshi, Watanabe Toshiaki, Sugai Tamotsu, Sugihara Ken-Ichi, Tsuruta Osamu, Hirata Ichiro, Hiwatashi Nobuo, Saito Hiroshi, Watanabe Mamoru, Sugano Kentaro, Shimosegawa Tooru
Guidelines Committee for creating and evaluating the "Evidence-based clinical practice guidelines for management of colorectal polyps", the Japanese Society of Gastroenterology (JSGE), K-18 Building 8F, 8-9-13 Ginza, Chuo, Tokyo, 104-0061, Japan,
J Gastroenterol. 2015 Mar;50(3):252-60. doi: 10.1007/s00535-014-1021-4. Epub 2015 Jan 7.
Recently in Japan, the morbidity of colorectal polyp has been increasing. As a result, a large number of cases of colorectal polyps that are diagnosed and treated using colonoscopy has now increased, and clinical guidelines are needed for endoscopic management and surveillance after treatment.
Three committees [the professional committee for making clinical questions (CQs) and statements by Japanese specialists, the expert panelist committee for rating statements by the modified Delphi method, and the evaluating committee by moderators] were organized. Ten specialists for colorectal polyp management extracted the specific clinical statements from articles published between 1983 and September 2011 obtained from PubMed and a secondary database, and developed the CQs and statements. Basically, statements were made according to the GRADE system. The expert panel individually rated the clinical statements using a modified Delphi approach, in which a clinical statement receiving a median score greater than seven on a nine-point scale from the panel was regarded as valid.
The professional committee created 91CQs and statements for the current concept and diagnosis/treatment of various colorectal polyps including epidemiology, screening, pathophysiology, definition and classification, diagnosis, treatment/management, practical treatment, complications and surveillance after treatment, and other colorectal lesions (submucosal tumors, nonneoplastic polyps, polyposis, hereditary tumors, ulcerative colitis-associated tumor/carcinoma).
After evaluation by the moderators, evidence-based clinical guidelines for management of colorectal polyps have been proposed for 2014.
近年来在日本，大肠息肉的发病率一直在上升。因此，现在通过结肠镜检查诊断和治疗的大肠息肉病例大量增加，治疗后的内镜管理和监测需要临床指南。
组织了三个委员会[由日本专家制定临床问题（CQs）和声明的专业委员会、通过改良德尔菲法对声明进行评分的专家小组成员委员会以及由主持人组成的评估委员会]。10名大肠息肉管理专家从1983年至2011年9月发表于PubMed及一个二级数据库的文章中提取具体临床声明，并制定了CQs和声明。声明基本按照GRADE系统制定。专家小组采用改良德尔菲法对临床声明进行单独评分，其中在九点量表上获得中位数评分大于7分的临床声明被视为有效。
专业委员会针对各种大肠息肉的当前概念及诊断/治疗创建了91个CQs和声明，包括流行病学、筛查、病理生理学、定义和分类、诊断、治疗/管理、实际治疗、并发症及治疗后监测，以及其他大肠病变（黏膜下肿瘤、非肿瘤性息肉、息肉病、遗传性肿瘤、溃疡性结肠炎相关肿瘤/癌）。
经主持人评估后，已提出2014年基于证据的大肠息肉管理临床指南。
