He Feng, Dong Fangtian, Yu Weihong, Dai Rongping
Ophthalmic Surg Lasers Imaging Retina. 2015 Jan;46(1):44-8. doi: 10.3928/23258160-20150101-07.
Studies using sterilized air in chronic idiopathic macular holes show varying success rates, and the impact of a shorter duration of tamponade on photoreceptor layer recovery is not fully elucidated.
Surgical outcomes of 35 cases (seven in stage 3 and 28 in stage 4) were assessed for best corrected visual acuity and with spectral-domain optical coherence tomography.
The primary closure rate was 91.4%, and the closed cases and unclosed cases were significantly different in the preoperative (P = .042) and postoperative (P = .040) diameter of the photoreceptor layer defect. After surgery, there was a significant improvement in best corrected visual acuity and a decrease in the photoreceptor layer defect. The postoperative logarithm of the minimal angle of resolution was significantly correlated with the preoperative hole diameter (P = .003) and the postoperative diameter of the photoreceptor layer defect (P = .005).
Air tamponade is a safe and effective treatment for chronic and severe macular holes, with several spectral-domain optical coherence tomography parameters highly predictive of postoperative visual acuity.
在慢性特发性黄斑裂孔中使用无菌空气的研究显示成功率各异，且较短时间的填塞对光感受器层恢复的影响尚未完全阐明。
评估了35例患者（3期7例，4期28例）的手术结果，包括最佳矫正视力和使用光谱域光学相干断层扫描进行评估。
一期闭合率为91.4%，闭合病例与未闭合病例在术前（P = .042）和术后（P = .040）光感受器层缺损直径方面存在显著差异。术后，最佳矫正视力有显著改善，光感受器层缺损减小。术后最小分辨角对数与术前裂孔直径（P = .003）及术后光感受器层缺损直径（P = .005）显著相关。
空气填塞是治疗慢性重度黄斑裂孔的一种安全有效的方法，有几个光谱域光学相干断层扫描参数对术后视力具有高度预测性。
