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[成熟卵巢畸胎瘤中神经外胚层成分的形态学分析]

[Morphologic analysis of neuroectodermal elements in mature ovarian teratomas].

作者信息

Sobolewska G

机构信息

Patologisch-Anatomischen Abteilung, Instituts für Geburtshilfe und Frauenheilkunde der Medizinischen Akademie, Gdańsk.

出版信息

Zentralbl Gynakol. 1989;111(18):1246-52.

PMID:2555981
Abstract

Morphologic analysis of neuroectodermal glial tissue was studied in 43 cases of mature cystic teratomas of the ovary. During investigations it was stated that the borders of glial tissue within teratoma, in relation to surrounding mesenchymal structures, are different. Sometimes the glial nests revealed invasive growth in spite of their histologic maturity, while others had insular, polycyclic shapes and sharp borders. These first nests, according to opinion of the author, seem to be potential source of peritoneal infiltration in the cases of peritoneal gliomatosis. Some histologic structures, observed by the author, suggest that during the differentiation of teratoma of the ovary there are morphogenetic movements similar to those known from embryo- or histogenesis, like abortive migration of glial cells to form abortive cerebral cortex.

摘要

对43例卵巢成熟囊性畸胎瘤中的神经外胚层胶质组织进行了形态学分析。在研究过程中发现,畸胎瘤内胶质组织与周围间充质结构的边界各不相同。有时,胶质巢尽管组织学成熟,但仍显示浸润性生长,而其他胶质巢则呈岛状、多环状且边界清晰。据作者观点,这些最初的巢似乎是腹膜胶质瘤病病例中腹膜浸润的潜在来源。作者观察到的一些组织结构表明,在卵巢畸胎瘤的分化过程中,存在与胚胎发育或组织发生中已知的形态发生运动相似的情况,比如胶质细胞的异常迁移以形成异常的大脑皮层。

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