Institute for Bioengineering of Catalonia (IBEC). Baldiri Reixac 15-21, 08028, Barcelona, Spain.
Departament de Microbiologia, Universitat de Barcelona, 08028, Barcelona, Spain.
Trends Microbiol. 2015 Feb;23(2):67-9. doi: 10.1016/j.tim.2014.12.009. Epub 2015 Jan 2.
The nucleoid-associated protein H-NS silences unwanted expression of acquired foreign DNA. Ali and colleagues recently identified which horizontally-acquired genes are targeted by H-NS in Salmonella to avoid fitness loss. The reported data strengthen our view about the role of H-NS in bacterial evolution driven by horizontal gene transfer.
类核相关蛋白 H-NS 沉默外来 DNA 的非必要表达。Ali 及其同事最近确定了沙门氏菌中 H-NS 靶向的水平获得性基因，以避免适应度损失。报道的数据加强了我们对 H-NS 在水平基因转移驱动的细菌进化中的作用的看法。
