Baneth Gad, Harrus Shimon, Gal Arnon, Aroch Itamar
Koret School of Veterinary Medicine, Hebrew University, Rehovot, Israel.
Koret School of Veterinary Medicine, Hebrew University, Rehovot, Israel.
Vet Parasitol. 2015 Feb 28;208(1-2):30-4. doi: 10.1016/j.vetpar.2014.12.013. Epub 2014 Dec 23.
The protozoon Hepatozoon canis and the rickettsia Ehrlichia canis are tick-borne pathogens, transmitted by Rhipicephalus sanguineus, which cause canine hepatozoonosis and canine monocytic ehrlichiosis, respectively. Co-infection of the same host monocytes with H. canis and E. canis confirmed by molecular characterization of the infecting agents and quantitative assessment of co-infected cells is described for the first time in three naturally-infected dogs. Blood smear evaluation indicated that at least 50% of the leukocytes infected with H. canis gamonts contained E. canis morulae. Co-infection of the same host cell demonstrated in this report suggests that infection with one pathogen may permit or enhance invasion or prolonged cellular survival of the other.
原虫犬肝簇虫和立克次氏体犬埃立克体是蜱传播的病原体，由血红扇头蜱传播，分别引起犬肝簇虫病和犬单核细胞埃立克体病。首次在三只自然感染的犬中描述了通过感染因子的分子特征和共感染细胞的定量评估证实犬肝簇虫和犬埃立克体在同一宿主单核细胞中的共感染情况。血液涂片评估表明，至少50%感染犬肝簇虫配子体的白细胞含有犬埃立克体桑葚体。本报告中证实的同一宿主细胞的共感染表明，感染一种病原体可能会允许或增强另一种病原体的侵入或延长其在细胞内的存活时间。
