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Antibiotics: An irresistible newcomer.

作者信息

Wright Gerard

机构信息

Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario L8N 3Z5, Canada.

出版信息

Nature. 2015 Jan 22;517(7535):442-4. doi: 10.1038/nature14193. Epub 2015 Jan 7.

DOI:10.1038/nature14193

PMID:25561172

Abstract

摘要

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Systematic Mutagenesis of Oncocin Reveals Enhanced Activity and Insights into the Mechanisms of Antimicrobial Activity.

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本文引用的文献

A new antibiotic kills pathogens without detectable resistance.

Nature. 2015 Jan 22;517(7535):455-9. doi: 10.1038/nature14098. Epub 2015 Jan 7.

Prioritized current unmet needs for antibacterial therapies.

Clin Pharmacol Ther. 2014 Aug;96(2):151-3. doi: 10.1038/clpt.2014.106.

Something old, something new: revisiting natural products in antibiotic drug discovery.

Can J Microbiol. 2014 Mar;60(3):147-54. doi: 10.1139/cjm-2014-0063. Epub 2014 Jan 22.

Insights into the phylogeny and coding potential of microbial dark matter.

Nature. 2013 Jul 25;499(7459):431-7. doi: 10.1038/nature12352. Epub 2013 Jul 14.

Platforms for antibiotic discovery.

Nat Rev Drug Discov. 2013 May;12(5):371-87. doi: 10.1038/nrd3975.

Is the GAIN Act a turning point in new antibiotic discovery?

Can J Microbiol. 2013 Mar;59(3):153-6. doi: 10.1139/cjm-2013-0089. Epub 2013 Feb 6.

Challenges of antibacterial discovery.

Clin Microbiol Rev. 2011 Jan;24(1):71-109. doi: 10.1128/CMR.00030-10.

Use of ichip for high-throughput in situ cultivation of "uncultivable" microbial species.

Appl Environ Microbiol. 2010 Apr;76(8):2445-50. doi: 10.1128/AEM.01754-09. Epub 2010 Feb 19.

Drugs for bad bugs: confronting the challenges of antibacterial discovery.

Nat Rev Drug Discov. 2007 Jan;6(1):29-40. doi: 10.1038/nrd2201. Epub 2006 Dec 8.

Glycopeptide antibiotic resistance genes in glycopeptide-producing organisms.

Antimicrob Agents Chemother. 1998 Sep;42(9):2215-20. doi: 10.1128/AAC.42.9.2215.

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相似文献

Antibiotics: An irresistible newcomer.

Nature. 2015 Jan 22;517(7535):442-4. doi: 10.1038/nature14193. Epub 2015 Jan 7.

Bacteria: Assessing resistance to new antibiotics.

Nature. 2015 Mar 12;519(7542):158. doi: 10.1038/519158e.

Antibacterial drugs: a new drug for resistant bugs.

Nat Rev Drug Discov. 2015 Feb;14(2):94. doi: 10.1038/nrd4544.

Drug discovery: Early antibiotic from a cranberry bog.

Nature. 2015 Feb 19;518(7539):303. doi: 10.1038/518303a.

A new antibiotic kills pathogens without detectable resistance.

Nature. 2015 Jan 22;517(7535):455-9. doi: 10.1038/nature14098. Epub 2015 Jan 7.

Teixobactin and Its Analogues: A New Hope in Antibiotic Discovery.

ACS Infect Dis. 2017 Oct 13;3(10):688-690. doi: 10.1021/acsinfecdis.7b00108. Epub 2017 Aug 3.

Diphenyleneiodonium chloride (DPIC) displays broad-spectrum bactericidal activity.

Sci Rep. 2017 Sep 14;7(1):11521. doi: 10.1038/s41598-017-11575-5.

A new antibiotic and the evolution of resistance.

N Engl J Med. 2015 Mar 19;372(12):1168-70. doi: 10.1056/NEJMcibr1500292.

Synthesis and antibacterial activity of tripropeptin C derivatives modified at the carboxyl groups.

J Antibiot (Tokyo). 2014 Mar;67(3):265-8. doi: 10.1038/ja.2013.128. Epub 2013 Dec 4.

Repurposing ethyl bromopyruvate as a broad-spectrum antibacterial.

J Antimicrob Chemother. 2019 Apr 1;74(4):912-920. doi: 10.1093/jac/dky555.

引用本文的文献

Enhanced Bioactivity of Tailor-Made Glycolipid Enriched Manuka Honey.

Int J Mol Sci. 2022 Oct 10;23(19):12031. doi: 10.3390/ijms231912031.

Bacterial Natural Product Drug Discovery for New Antibiotics: Strategies for Tackling the Problem of Antibiotic Resistance by Efficient Bioprospecting.

Antibiotics (Basel). 2021 Jul 10;10(7):842. doi: 10.3390/antibiotics10070842.

Emerging peptide antibiotics with therapeutic potential.

Med Drug Discov. 2021 Mar;9:100078. doi: 10.1016/j.medidd.2020.100078. Epub 2020 Dec 30.

Metallo-β-Lactamase Inhibitors Inspired on Snapshots from the Catalytic Mechanism.

Biomolecules. 2020 Jun 3;10(6):854. doi: 10.3390/biom10060854.

Leveraging phytochemicals: the plant phylogeny predicts sources of novel antibacterial compounds.

Future Sci OA. 2019 Jul 25;5(7):FSO407. doi: 10.2144/fsoa-2018-0124.

Systematic Mutagenesis of Oncocin Reveals Enhanced Activity and Insights into the Mechanisms of Antimicrobial Activity.

Mol Syst Des Eng. 2018 Dec 1;3(6):930-941. doi: 10.1039/C8ME00051D. Epub 2018 Oct 8.

Elucidation of the Teixobactin Pharmacophore.

ACS Chem Biol. 2016 Jul 15;11(7):1823-6. doi: 10.1021/acschembio.6b00295. Epub 2016 Jun 3.

Discovery of microbial natural products by activation of silent biosynthetic gene clusters.

Nat Rev Microbiol. 2015 Aug;13(8):509-23. doi: 10.1038/nrmicro3496. Epub 2015 Jun 29.

Teixobactin: a novel antibiotic in treatment of gram positive bacterial infections.

J Clin Diagn Res. 2015 Mar;9(3):DL01. doi: 10.7860/JCDR/2015/13033.5720. Epub 2015 Mar 1.

本文引用的文献

A new antibiotic kills pathogens without detectable resistance.

Nature. 2015 Jan 22;517(7535):455-9. doi: 10.1038/nature14098. Epub 2015 Jan 7.

Prioritized current unmet needs for antibacterial therapies.

Clin Pharmacol Ther. 2014 Aug;96(2):151-3. doi: 10.1038/clpt.2014.106.

Something old, something new: revisiting natural products in antibiotic drug discovery.

Can J Microbiol. 2014 Mar;60(3):147-54. doi: 10.1139/cjm-2014-0063. Epub 2014 Jan 22.

Insights into the phylogeny and coding potential of microbial dark matter.

Nature. 2013 Jul 25;499(7459):431-7. doi: 10.1038/nature12352. Epub 2013 Jul 14.

Platforms for antibiotic discovery.

Nat Rev Drug Discov. 2013 May;12(5):371-87. doi: 10.1038/nrd3975.

Is the GAIN Act a turning point in new antibiotic discovery?

Can J Microbiol. 2013 Mar;59(3):153-6. doi: 10.1139/cjm-2013-0089. Epub 2013 Feb 6.

Challenges of antibacterial discovery.

Clin Microbiol Rev. 2011 Jan;24(1):71-109. doi: 10.1128/CMR.00030-10.

Use of ichip for high-throughput in situ cultivation of "uncultivable" microbial species.

Appl Environ Microbiol. 2010 Apr;76(8):2445-50. doi: 10.1128/AEM.01754-09. Epub 2010 Feb 19.

Drugs for bad bugs: confronting the challenges of antibacterial discovery.

Nat Rev Drug Discov. 2007 Jan;6(1):29-40. doi: 10.1038/nrd2201. Epub 2006 Dec 8.

Glycopeptide antibiotic resistance genes in glycopeptide-producing organisms.

Antimicrob Agents Chemother. 1998 Sep;42(9):2215-20. doi: 10.1128/AAC.42.9.2215.

Suppr超能文献

Antibiotics: An irresistible newcomer.

作者信息

机构信息

出版信息

相似文献

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