Pan Cunxue, Azhati Gulina, Xing Yan, Wang Yan, Liu Wenya
Imaging Center, First Teaching Hospital of Xingjiang Medical University, Urumqi, Xinjiang 830054, China.
Chin Med J (Engl). 2015 Jan 5;128(1):15-9. doi: 10.4103/0366-6999.147787.
The incidence of congenital coronary artery anomalies (CCAAs) is different between ethnic groups, but there is no report about Uyghur CCAAs because of the limitation of inspection methods. This study determined the prevalence of Uyghur CCAAs and analysis the difference of CCAAs between Uyghur and Han ethnic groups by the method of multi-slice computed tomography coronary angiography (MSCTCA).
Seven thousand four hundred and sixty-nine MSCTCA were analyzed for the CCAAs retroactively, 1934 were Uyghur patients while 4746 were Han patients. All the coronary artery images dates obtained by MSCTCA were evaluated for the CCAAs by two doctors.
Nineteen kinds of CCAAs were found: (1) The overall incidence of CCAAs was 2.72% (203/7469) among all patients, 2.34% (111/4746) among Han patients whereas a significant higher 3.93% (76/1934) among Uyghur patients (χ2 = 12.780,P < 0.05); (2) the incidence of CCAAs among male patients was 2.48% (76/3069) in Han while 4.33% (56/1293) in Uyghur (χ2 = 10.663, P < 0.05); (3) the incidence of CCAAs on the left side was 1.07% (51/4746) among Han patients while 2.17% (42/934) among Uyghur patients (χ2 = 12.047, P < 0.05); (4) among these 19 kinds of CCAAs, there were significant differences of the incidence of the following kinds of CCAAs between Uyghur and Han: Left coronary artery (LCA) high location (χ2 = 8.320, P = 0.004), right coronary artery (RCA) originate from left coronary sinus (χ2 = 5.450, P = 0.020), and RCA originate from left Coronary sinus + LCA high location (P = 0.024).
There exists some difference in CCAAs between Uyghur and Han ethnic groups. The CCAAs incidence of Uyghur is higher than that of Han, especially in male patients and on the left side; among all kinds of CCAAs, the incidence of LCA high location, RCA originate from left coronary sinus, RCA originate from left coronary sinus + LCA high locations of Uyghur is higher than Han.
先天性冠状动脉异常（CCAA）的发病率在不同种族之间存在差异，但由于检查方法的限制，尚无关于维吾尔族CCAA的报道。本研究采用多层螺旋CT冠状动脉造影（MSCTCA）方法确定维吾尔族CCAA的患病率，并分析维吾尔族和汉族之间CCAA的差异。
回顾性分析7469例MSCTCA检查结果，其中维吾尔族患者1934例，汉族患者4746例。由两名医生对所有通过MSCTCA获得的冠状动脉图像数据进行CCAA评估。
共发现19种CCAA：（1）所有患者中CCAA的总体发生率为2.72%（203/7469），汉族患者中为2.34%（111/4746），而维吾尔族患者中显著更高，为3.93%（76/1934）（χ2 = 12.780，P < 0.05）；（2）汉族男性患者中CCAA的发生率为2.48%（76/3069），维吾尔族男性患者中为4.33%（56/1293）（χ2 = 10.663，P < 0.05）；（3）汉族患者左侧CCAA的发生率为1.07%（51/4746），维吾尔族患者中为2.17%（42/934）（χ2 = 12.047，P < 0.05）；（4）在这19种CCAA中，维吾尔族和汉族之间以下几种CCAA的发生率存在显著差异：左冠状动脉（LCA）高位（χ2 = 8.320，P = 0.004）、右冠状动脉（RCA）起源于左冠状窦（χ2 = 5.450，P = 0.020）以及RCA起源于左冠状窦+LCA高位（P = 0.024）。
维吾尔族和汉族之间在CCAA方面存在一些差异。维吾尔族CCAA的发生率高于汉族，尤其是男性患者和左侧；在所有类型的CCAA中，维吾尔族LCA高位、RCA起源于左冠状窦、RCA起源于左冠状窦+LCA高位的发生率高于汉族。
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