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美国银屑病的经济负担:系统评价。

Economic Burden of Psoriasis in the United States: A Systematic Review.

机构信息

Department of Dermatology, University of California Davis, Sacramento.

Department of Dermatology, University of Colorado Denver.

出版信息

JAMA Dermatol. 2015 Jun;151(6):651-8. doi: 10.1001/jamadermatol.2014.3593.

DOI:10.1001/jamadermatol.2014.3593
PMID:25565304
Abstract

IMPORTANCE

The total cost of psoriasis in the United States is unknown. Defining the US economic burden of psoriasis is needed because it provides the foundation for research, advocacy, and educational efforts.

OBJECTIVE

To determine the US economic burden of psoriasis from a societal perspective.

EVIDENCE REVIEW

PubMed and MEDLINE databases were searched between January 1, 2008, and September 20, 2013, for economic investigations on the direct, indirect, intangible, and comorbidity costs of adult psoriasis in the United States. The base year costs were adjusted to 2013 US dollars using the Consumer Price Index for All Urban Consumers and multiplied by the estimated number of US patients with psoriasis in 2013 to determine the 2013 psoriasis cost burden.

FINDINGS

Among 100 identified articles, 22 studies were included in the systematic review. The direct psoriasis costs ranged from $51.7 billion to $63.2 billion, the indirect costs ranged from $23.9 billion to $35.4 billion, and medical comorbidities were estimated to contribute $36.4 billion annually in 2013 US dollars. Patients with psoriasis would pay a lifetime cost of $11,498 for relief of physical symptoms and emotional health; however, intangible cost data are limited. The annual US cost of psoriasis amounted to approximately $112 billion in 2013.

CONCLUSIONS AND RELEVANCE

The economic burden of psoriasis is substantial and significant in the United States.

摘要

重要性

美国的银屑病总费用尚不清楚。定义美国银屑病的经济负担是必要的,因为它为研究、宣传和教育工作提供了基础。

目的

从社会角度确定美国银屑病的经济负担。

证据回顾

2008 年 1 月 1 日至 2013 年 9 月 20 日,我们在 PubMed 和 MEDLINE 数据库中检索了关于美国成人银屑病直接、间接、无形和合并症成本的经济调查,从社会角度确定美国银屑病的经济负担。使用所有城市消费者的消费者价格指数调整基础年成本,并乘以 2013 年美国银屑病患者的估计数量,以确定 2013 年银屑病的成本负担。

发现

在 100 篇确定的文章中,有 22 项研究被纳入系统综述。直接银屑病成本范围为 517 亿至 632 亿美元,间接成本范围为 239 亿至 354 亿美元,2013 年医疗合并症每年估计贡献 364 亿美元。银屑病患者将支付 11498 美元的终生费用,以缓解身体症状和情绪健康;然而,无形成本数据有限。2013 年,美国银屑病的年费用约为 1120 亿美元。

结论和相关性

美国银屑病的经济负担是巨大的,也是显著的。

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