Patten Scott B, Williams Jeanne V A, Lavorato Dina H, Fiest Kirsten M, Bulloch Andrew G M, Wang Jianli
Professor, Department of Community Health Sciences, University of Calgary, Calgary, Alberta; Member, Mathison Centre for Mental Health Research and Education, Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta.
Research Associate, Department of Community Health Sciences, University of Calgary, Calgary, Alberta.
Can J Psychiatry. 2014 Nov;59(11):609-14. doi: 10.1177/070674371405901107.
Large increases in the use of antidepressants (ADs) were reported in the past 2 decades in many countries, including Canada. Our objective was to determine whether this pattern of increasing use has continued, using data from a 2012 national mental health survey.
During the past 2 decades, a series of Canadian national health surveys have evaluated AD use in the household population. Some of these surveys have assessed past 2-day use whereas others have assessed self-reported past-month use. We applied meta-regression methods as a methodological strategy to address this heterogeneity and to examine long-term trends, incorporating 2012 data.
In keeping with prior reports, AD use rapidly increased in the 1990s and early 2000s. However, the 2012 data suggest that these increases have slowed or perhaps even stopped in recent years. A post hoc examination of longitudinal data from the National Population Health Survey reinforced the impression of a levelling off in the use of these medications.
The frequency of AD use may now be stabilizing in the Canadian population. This emerging steady state may reflect a contemporary balance between the perceived need, perceived effectiveness, and acceptability of these medications in the general population.
过去20年里，包括加拿大在内的许多国家都报告了抗抑郁药（ADs）使用量的大幅增加。我们的目的是利用2012年全国心理健康调查的数据，确定这种使用增加的模式是否仍在持续。
在过去20年里，一系列加拿大全国性健康调查评估了家庭人口中抗抑郁药的使用情况。其中一些调查评估了过去两天的使用情况，而其他调查则评估了自我报告的过去一个月的使用情况。我们应用元回归方法作为一种方法策略来解决这种异质性，并结合2012年的数据研究长期趋势。
与先前的报告一致，抗抑郁药的使用在20世纪90年代和21世纪初迅速增加。然而，2012年的数据表明，近年来这种增加已经放缓甚至可能已经停止。对全国人口健康调查纵向数据的事后分析强化了这些药物使用趋于平稳的印象。
加拿大人口中抗抑郁药的使用频率现在可能趋于稳定。这种新出现的稳定状态可能反映了普通人群对这些药物的感知需求、感知有效性和可接受性之间的当代平衡。
