Institute for Mental Health Policy Research, Centre for Addiction and Mental Health (CAMH), 100 Collip Circle, Suite 200, ON, N6G 4X8, London, Canada.
Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada.
Can J Public Health. 2021 Oct;112(5):919-926. doi: 10.17269/s41997-021-00526-3. Epub 2021 Jun 2.
This study investigated the rates of and change in past-year antidepressant use from 1999 to 2017 among a representative sample of Ontario adults and past-year alcohol users and problem drinkers. It examined whether alcohol use and problem drinking are associated with antidepressant use over time, whether gender moderated the effect of problem drinking on antidepressant use, and the potential correlates of past-year antidepressant use.
This study utilized data from the Centre for Addiction and Mental Health Monitor study, a repeat cross-sectional telephone survey of the Ontario general adult population. Data are from 15 annual cycles of the survey 1999-2017 (where relevant variables were included), resulting in a sample size of N = 35,210. Variables of interest included demographic variables, past-year antidepressant use, past-year alcohol use, and past-year problem drinking (e.g., 8+ on the Alcohol Use Disorders Identification Test).
Past-year antidepressant use increased from 1999 to 2017 similarly among the full sample, past-year alcohol users, and past-year problem drinkers. Approximately 9% of Ontarians reported past-year antidepressant use in 2017. Overall, past-year problem drinkers were 1.5 times more likely to use antidepressants than non-problem drinkers. Past-year alcohol use was not associated with antidepressant use. Gender moderated the association between past-year problem drinking and antidepressant use.
This study determined that past-year antidepressant use increased from 1999 to 2017, that past-year problem drinkers are more likely to use antidepressants than non-problem drinkers, and that past-year problem drinking is associated with past-year antidepressant use among women but not among men.
本研究调查了来自安大略省成年人代表性样本的过去一年抗抑郁药使用率和变化，以及过去一年的酒精使用者和问题饮酒者。它研究了随着时间的推移，酒精使用和问题饮酒是否与抗抑郁药的使用有关，问题饮酒对抗抑郁药使用的影响是否因性别而异，以及过去一年抗抑郁药使用的潜在相关因素。
本研究利用成瘾与心理健康监测中心研究的数据，这是一项对安大略省普通成年人群进行的重复横断面电话调查。数据来自该调查的 15 个年度周期（1999-2017 年）（在相关变量被包括的情况下），样本量为 N=35210。感兴趣的变量包括人口统计学变量、过去一年的抗抑郁药使用情况、过去一年的酒精使用情况和过去一年的问题饮酒情况（例如，酒精使用障碍识别测试中的 8+）。
在整个样本、过去一年的酒精使用者和过去一年的问题饮酒者中，过去一年抗抑郁药的使用从 1999 年到 2017 年相似地增加。大约 9%的安大略省人在 2017 年报告过去一年使用过抗抑郁药。总的来说，过去一年的问题饮酒者使用抗抑郁药的可能性是没有问题饮酒者的 1.5 倍。过去一年的酒精使用与抗抑郁药的使用无关。性别调节了过去一年问题饮酒与抗抑郁药使用之间的关联。
本研究确定，过去一年抗抑郁药的使用从 1999 年到 2017 年增加，过去一年的问题饮酒者比非问题饮酒者更有可能使用抗抑郁药，而且过去一年的问题饮酒与女性的过去一年抗抑郁药使用有关，但与男性无关。
