Verkerk K, Luijsterburg P A J, Heymans M W, Ronchetti I, Pool-Goudzwaard A L, Miedema H S, Koes B W
Rotterdam University of Applied Sciences, The Netherlands.
Spine & Joint Centre, Rotterdam, The Netherlands.
Eur J Pain. 2015 Sep;19(8):1101-10. doi: 10.1002/ejp.633. Epub 2015 Jan 6.
It remains unclear to what extent patients recover from chronic non-specific low back pain (NSLBP). The objective of this study was to determine (1) the course of chronic NSLBP in tertiary care and (2) which factors predicted 5- and 12-month outcomes.
This prospective study includes 1760 chronic NSLBP patients from a rehabilitation clinic (mean age 40.1 years, SD 10.6). After baseline measurement, patients followed a 2-month multidisciplinary therapy programme; evaluation took place at 2, 5 and 12 months post baseline. Recovery was defined as (1) relative recovery [30% improvement on the pain, visual analogue scale (VAS) compared with baseline] and (2) absolute recovery (VAS pain ≤ 10 mm). The multivariate logistic regression analysis included 23 baseline characteristics.
Patient-reported intensity of back pain decreased from 55.5 (SD 23.0) at baseline to 37.0 (SD 23.8), 35.3 (SD 26.1) and 32.3 (SD 26.9) at 2-, 5- and 12-month follow-up, respectively. Younger age, back pain at baseline, no psychological/physical dysfunction (Symptom Check List-90, item 9), and higher baseline scores on the physical component scale and mental component scale of quality of life (Short Form-36) were positively associated with recovery at 5 and 12 months. At 5-month follow-up, higher work participation at baseline was also a prognostic factor for both definitions of recovery. At 12-month follow-up, having co-morbidity was predictive for both definitions.
The results of this study indicate that in chronic NSLBP patients, bio-psychosocial prognostic factors may be important for clinicians when predicting recovery in back pain intensity during a 1-year period.
慢性非特异性下背痛(NSLBP)患者的恢复程度仍不清楚。本研究的目的是确定:(1)三级医疗中慢性NSLBP的病程;(2)哪些因素可预测5个月和12个月的预后。
这项前瞻性研究纳入了一家康复诊所的1760例慢性NSLBP患者(平均年龄40.1岁,标准差10.6)。在基线测量后,患者接受了为期2个月的多学科治疗方案;在基线后2、5和12个月进行评估。恢复定义为:(1)相对恢复[疼痛视觉模拟量表(VAS)较基线改善30%];(2)绝对恢复(VAS疼痛≤10mm)。多变量逻辑回归分析纳入了23项基线特征。
患者报告的背痛强度从基线时的55.5(标准差23.0)分别降至2个月、5个月和12个月随访时的37.0(标准差23.8)、35.3(标准差26.1)和32.3(标准差26.9)。年龄较小、基线时背痛、无心理/身体功能障碍(症状自评量表90项中的第9项)以及生活质量(简明健康状况调查问卷)身体成分量表和精神成分量表的基线得分较高与5个月和12个月时的恢复呈正相关。在5个月随访时,基线时较高的工作参与度也是两种恢复定义的预后因素。在12个月随访时,有合并症对两种恢复定义均有预测作用。
本研究结果表明,对于慢性NSLBP患者,生物心理社会预后因素对临床医生预测1年内背痛强度的恢复可能很重要。